3' ends of eukaryotic mRNAs can undergo processing events that include endonucleolytic cleavage and polyadenylation. Cleavage and polyadenyla- tion specificity factors (CPSF) mediate 3' cleavage of the transcript and sub- sequent polyadenylation. CPSF6, also known as CF Im68 (mammalian cleavage ...
2025年1月13日,苏州大学徐杨、吴德沛及陈苏宁共同通讯在Nature communications上在线发表题为“CPSF6-RARγ interacts with histone deacetylase 3 to promote myeloid transformation in RARG-fusion acute myeloid leukemia”的研究论文。研究...
CPSF6 (E4F5F) Rabbit mAb recognizes endogenous levels of total CPSF6 protein. Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu56 of human CPSF6 protein. ...
CPSF6 基因简介 中英文全称:断裂和聚腺苷酸化特异因子6, 68kDa cleavage and polyadenylation specific factor 6, 68kDa 分布:核 活性:核 苷酸结合|RNA 结合|蛋白结合 参与:mRNA 加工 OMIM/位置:604979 12q15
基因别名:4733401N12Rik; AI256641; CFIM; CFIM68; CPSF6; HPBRII-4; HPBRII-7 UniProt ID:(Human) Q16630,(Mouse) Q6NVF9 Entrez Gene ID:(Human) 11052,(Mouse) 432508 功能 nucleotide bindingRNA bindingmRNA bindingprotein bindingpoly(A) RNA bindingnucleic acid bindingRNA processing factor ...
单词 CPSF6 释义 CPSF6AcronymDefinition CPSF6 Cleavage and Polyadenylation Specific Factor 6 随便看 NHSMUN NHSN NHS (National Health Service) Institute for Innovation and Improvement NHSO NHSOA NHSOC NHSOG NHSOL NHSP NHSPA NH-SPA NHSPCA NHSPE NHSPL NHSPS NHSQ NHSQL NHSR NHSRA NHSRC NHSRF ...
CircCPSF6通过增强细胞增殖和迁移侵袭能力、推动体内成瘤和转移过程诱导了HCC细胞的恶性表型。机制上,circCPSF6通过竞争性结合PCBP2抑制了YAP1的降解,从而提高YAP1表达水平并激活YAP通路,最终导致肿瘤进展。本研究表明m6A修饰的circCPSF6在...
产品名称 Recombinant CPSF6 Antibody 别名 剪切及多聚腺苷酸化特异性因子6蛋白抗体 | 剪切及多聚腺苷酸化特异性因子6蛋白抗体 | 重组CPSF6抗体 英文别名 CFIm68 | Cleavage and polyadenylation specificity factor 68 kDa subunit | Cleavage and polyadenylation specificity factor subunit 6 | CPSF 68 kDa su...
通过在Cpsf6基因exon 2-3两侧分别插入loxP位点。该flox小鼠可与组织特异性Cre工具鼠交配,获得在特定细胞类型或组织中敲除Cpsf6基因的小鼠模型。 *使用本品系发表的文献需注明: Cpsf6-Flox mice (Cat. NO. NM-CKO-242000) were purchased from Shanghai Model Organisms Center, Inc.. ...