copper‐catalyzed ‘click’ chemistry for surface engineeringalkyne or azide‐functionalized surface synthesisself‐assembled monolayers of alkanethiolatessurface modification or functionalization via covalent couplingalkyne–azide click reaction and high reactivity in heterogeneous reaction systems...
Copper-catalyzed azide–alkyne cycloadditionclick chemistryhybrid networksnanocompositesphotoinduced reactionspolyhedral oligomeric silsesquioxaneAn efficient approach for the preparation of inorganic/organic hybrid thermosets via photoinduced copper-catalyzed azide–alkyne cycloaddition click chemistry is established. ...
Copper-free click chemistry in Applications Copper-free click chemistry reactions include cycloadditions for bioconjugation that do not rely on the use of transition metal catalyst, as opposed to traditional copper catalyzed сlick chemistry. These reactions include the strain promoted alkyne-azide ...
Díaz DD, Rajagopal K, Strable E, Schneider J, Finn MG (2006) “Click” chemistry in a supramolecular environment: stabilization of organogels by copper(I)-catalyzed azide-alkyne [3+2] cycloaddition. J Am Chem Soc 128:6056–6057Díaz, D. D.,Rajagopal, K.,Strable, E.,Schneider, J.,...
Y. Zhou, Z. Ma, A novel fluorescence enhanced route to detect copper(II) by click chemistry-catalyzed connection of Au@SiO2 and carbon dots, Sens. Actuators B: Chem. 233 (2016) 426-430.Y. Zhou, Z.F. Ma, A novel fluorescence enhanced route to detect copper(II) by click chemistry-...
[2+3]cycloaddition strategy relies on the use of strained cyclooctynes.Their use decreases the activation energy for the cycloaddition click reaction,enabling it to be carried out without the need for catalysis at low temperatures with an efficiency greater than that of the Cu(I)-catalyzed ...
Herein, to fully leverage a third aspect of molecular diversity enabled by the selenium–nitrogen exchange (SeNEx) reaction between alkynes and benzoselenazolones, a novel CuI‐catalyzed three‐component reaction has been successfully developed. This reaction integrates SeNEx with CuAAC ...
BTTES is a a next-generation, water-soluble ligand for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that accelerates reaction rates and suppresses cell cytotoxicity. The biocompatibility and fast kinetics of BTTES are advancements from water-insoluble TBTA and are desirable for bioconju...
Barry,Fokin Valery V.Efficiency and fidelity in a click-chemistry route to triazole dendrimers by the copper (I)-catalyzed ligation of azides and alkynes. Angewandte Chemie International Edition . 2004Wu, P.; Feldman, A.K.; Nugent, A.K.; Hawker, C.J.; Scheel, A.; Voit, B.; Pyun,...
is a widely used molecule in click chemistry reactions. Compared with traditional copper catalyzed click reactions, the click reactions involving DBCO do not require the participation of copper ions, thus avoiding the potential toxicity issues caused by copper ions and making the reaction conditions mil...