Copper-catalyzed "click" reaction/direct arylation sequence: modular syntheses of 1,2,3-triazoles. Org. Lett. 2008, 10, 3081-3084.Ackermann L.,Potukuchi H. K.,Landsberg D.,Vicente R.Copper-Catalyzed "Click" Reaction/Direct Arylation Sequence:Modular Syntheses of 1,2,3-Triazoles. Organic ...
Enhanced copper-catalyzed “click” reaction between homopolymers with terminal azide and alkyne groups in the presence of waterEnhanced copper-catalyzed “click” reaction between homopolymers with terminal azide and alkyne groups in the presence of water“Click” chemistryRole...
trifluoroacetic anhydride-promoted copper(i)-catalyzed interrupted click reaction from 1,2,3-triazoles to 3-trifluoromethyl-substituted 1,2,4-triaz 热度: Copper(I)-CatalyzedAsymmetricReactionsInvolvingRadicals Qiang-ShuaiGu, ‡ Zhong-LiangLi,
Different from the traditional two-electron oxidative addition-transmetalation-reductive elimination coupling strategy, visible light has been successfully integrated into transition metal-catalyzed coupling reaction of propargylic alcohol derivatives highly selectively forming allenenitriles: specifically speaking, ...
The click reaction cocktail was prepared using the Click-iT EdU Imaging kit (Invitrogen, C10337) according to the manufacturer’s protocol. In a typical experiment we mixed 50 μl of 10× Click-iT reaction buffer with 20 μl of CuSO4 solution, 1 μl Alexa Fluor–azide, 50 μl...
The regioselectivity of the dinuclear-Cu(I)-catalyzed version of the Huisgen reaction, abbreviated in this paper to Cu2AAC, was analyzed using quantum topological methods in order to study how the electronic charge distribution evolved along different reaction paths. Electronic densities were computed ...
[2+3]cycloaddition strategy relies on the use of strained cyclooctynes.Their use decreases the activation energy for the cycloaddition click reaction,enabling it to be carried out without the need for catalysis at low temperatures with an efficiency greater than that of the Cu(I)-catalyzed ...
Combination of photoinduced copper(I) catalyzed click chemistry and photosol–gel reaction for the synthesis of hybrid materials benefits of copper catalyzed azide–alkyne cycloaddition (CuAAC), we investigate in this work a novel one-step methodology for preparing hybrid materials by combining photoindu...
A Microwave-assisted click chemistry synthesis of 1,4-disubstituted 1,2,3-triazoles via a copper(I)-catalyzed three-component reaction. Org. Lett. 6, 4223–4225 (2004). Article CAS PubMed Google Scholar Cintas, P., Barge, A., Tagliapietra, S., Boffa, L. & Cravotto, G. Alkyne–...
The catalytic mechanism for the copper-catalyzed alkyne/azide cycloaddition to form 1,2,3-triazoles. Full size image General procedure for Click reaction with organic halides or aryl azides NaN3 (72 mg, 1.1 mmol), benzyl bromide (119 mg, 1 mmol) or other aryl halides, and terminal alkyne ...