Replicative DNA polymerases cannot initiate DNA synthesis de novo and rely on dedicated RNA polymerases, primases, to generate a short primer. This primer is then extended by the DNA polymerase. In diverse archaeal species, the primase has long been know
PCR primers). Although, state-of-the-art deep learning models can improve the hit rate in future works, high throughput approaches such as ours enable achieving higher hit numbers. Additionally, in-house preparation of CFPS systems could reduce the cost of peptide production down to ~1$35,36...
were maintained > 8 fold in BPT5204 compared to TN1. The transcripts of other genes were maintained at higher levels in BPT5204 than TN1 genotype (Fig. 6G). Fig. 6 Response of ribosomal protein encoding genes in combined and individual pathogen and drought stress. A Multiple gene expressi...
irrespective of the amount of surrounding fibrin. The platelet–fibrin binding is probabilistic: the higher the fibrin density is and the more filopodia are formed, the more likely it is that they interact. The model implies that all filopodia are involved and this is a reasonable simplification...
Negative additive effects of the studied factors yield higher firing rates at a given input current in our pathophysiological influence model (Methods, Electrophysiological model). Thus, neuronal hyperexcitability seems to be associated with cognitive deterioration, according to our calculations. Table 1 ...
2022, Redox Biology Citation Excerpt : For proliferation, we found that the expression of PCNA protein increased under 5 mg/kg/d DEHP, but this did not change the placental pathology. Low-dose DEHP can promote cell proliferation, while high-dose DEHP inhibits cell proliferation [44]. This res...
encoding a V-type proton ATPase subunit F, should also be considered because its homologous genes in apple and orange have been reported to regulate citric acid content [44,45]. Expression profile ofPrupe.5G006500in an acid variety and a non-acid variety had a higher correlation with the ci...
The success rate for molecular identifications of the Lanashuaia II samples were comparable for ZooMS (35/38) and DNA (33/38 using cytb cetacean primers), with a slightly higher success rate for the collagen-based identification method. The advantage of ZooMS lay in its ability to identify ...
The fourth principal component had higher positive loadings for WLR (0.535), CGP (0.403), CD (0.438), and SBV (0.451) and higher negative loadings for HRR (−0.527), and BDV (−0.470); this PC is referred to as the width length rate factor. The fifth principal component had a ...
model predictions close to the decision cutoff are associated with a higher ambiguity. For such cases falling in the mid-range of the AI score, pathologists could integrate other factors such as clinical probability or imaging results to enhance the prediction confidence. Our software is currently ...