Furthermore, the performance of the mixture of these four strains was clearly improved, reaching the maximal removal efficiency of 64.1% also at the optimal temperature of 35 °C, which was 8.7% higher than that of the best individual stain. This improved was largely attributed to the mixed...
The therapeutic efficacy of tLNP/siHBV was evaluated in mouse models of HBV replication. Higher than 2log10IU/mL decrease of viral antigen (2.65log10reduction of HBsAg, 1.82log10reduction of HBeAg) and HBV DNA (2.29log10reduction) were observed after a single dose of tLNP/siHBV at the dos...
As several plasmids seemed to have a higher copy number compared to the main chromosome based on the read coverage of the Illumina data, we used a qPCR protocol to directly measure the number of DNA molecules present in a strain relative to the main chromosome. We chose to use plasmids cp2...
Compared with the pathological results, the concordance rate of 2D-US was 65.4%, whereas the concordance rate of CEUS was 75.9%, which was significantly higher than that of 2D-US. Other studies have also shown that CEUS has high sensitivity and specificity in diagnosing benign and malignant ...
It has been reported that Trx-1 levels are increased in several human tumors, and that higher Trx-1 levels are associated with more aggressive tumor growth [28], [29], [31]. We and others have shown that Au has antitumor activity, both in vitro and in vivo when combined with agents ...
excluding the ever-decreasing cost of DNA synthesis or alternatively using PCR primers). Although, state-of-the-art deep learning models can improve the hit rate in future works, high throughput approaches such as ours enable achieving higher hit numbers. Additionally, in-house preparation of CFPS...
miR-148b-3p was associated with significantly higher expression in patients with gain (Additional file6c;P = 0.002 andP = 0.008 in the discovery and replication cohorts, respectively). Overexpression of miR-148b-3p significantly increased cell proliferation in the KPL-4 cell line, and ...
In contrast, ERGO0B8162p has a higher amino acid identity to Pdr5p (53%) than to Snq2p (36%). A similar heterologous tandem in a similar neighborhood is observed for KLLA and SAKL with, however, the insertion of an increasing number of genes between the two members of the repeat. ...
intention-to-treat population was analyzed (CA-SAP [n = 51] versus SAP [n = 53]). The trial has met pre-specified endpoints. CA-SAP was associated with a significantly higher MPR rate (33.3%) than SAP (17.0%,P = 0.044). The CA-SAP group had a significantly higher ob...
Traces of Sulphur (S) and manganese (Mn) were observed on the wallpapers’ verso, although S was solely recognized in the not-written areas, except for INV_15, while a higher distribution of Ca and iron (Fe) was seen in this side as compared to the recto (Fig.6a, b, Supplementary ...