In this study, we analyze orphan non-coding RNAs (oncRNAs) from serum samples of 1050 individuals diagnosed with non-small cell lung cancer (NSCLC) at various stages, as well as sex-, age-, and BMI-matched controls. We demonstrate that our multi-task generative AI model, Orion, ...
Georgia, Augusta University, GA 30912, USA Abstract Recent advancements in genome-wide analyses and RNA-sequencing technologies led to the discovery of small noncoding RNAs, such as microRNAs (miRs), as well as both linear long noncoding RNAs (lncRNAs) and circular long noncoding RNAs (circRNAs...
Circulating exosome‐derived bona fide long non‐coding RNAs predicting the occurrence and metastasis of hepatocellular carcinomaexosomefingerprintlncRNAplasmarisk score analysisAlthough the diagnosis and therapy approach developed, techniques for the early diagnosis of HCC remain insufficient which results in ...
Circulating long noncoding RNA ZNFX1 antisenseRNA negatively correlates with disease risk,severity, inf l ammatory markers, and predictspoor prognosis in sepsis patientsYahuan Xu, MM a , Bibo Shao, MM b,∗AbstractThis study aimed to investigate the correlation of long noncoding RNA (lncRNA) ...
The present invention relates to a a method for predicting mortality of a test patient with acute kidney injury comprising (a) detecting the expression level of the non-coding RNA (ncRNA) of SEQ ID NO: 1 in a sample obtained from said test patient with acute kidney injury, (b) comparing...
Long noncoding RNAs (lncRNAs) play a vital role in tumorigenesis. Until now, the value of circulating lncRNAs in the diagnosis of breast cancer (BC) has remained unknown. Here, we have explored the clinical significance of lncRNAs GAS5 and H19 in BC patients. Total RNA in the plasma was...
Changes in human genome-wide long noncoding RNAs (lncRNAs)associatedwith air pollution are unknown. This study aimed to investigate theeffect of air pollut... X Du,Y Jiang,Q Zhang,... - 《Environmental Science & Technology》 被引量: 0发表: 2023年 Circulating Exosomal Gastric Cancer–Associate...
long noncoding RNAnon‐small cell lung cancerSOX2OTEarly diagnosis of NSCLC is essential for patient treatment and prognosis. lncRNA have potential roles in tumor initiation and differentiation. The objective of this study was to investigate whether the circulating lncRNA: GAS5 and SOX2OT could be...
Long noncoding RNAs in endometriosis: biological functions, expressions, and mechanisms J. Cell. Physiol., 236 (2021), pp. 6-14 Google Scholar Wang et al., 2015 Y. Wang, Y. Li, Z. Yang, K. Liu, D. Wang Genome-wide microarray analysis of long non-coding RNAs in eutopic secretory ...
The contribution of rare noncoding genetic variation to common phenotypes is largely unknown, as a result of a historical lack of population-scale whole-genome sequencing data and the difficulty of categorizing noncoding variants into functionally simila