Biochemistry Chromatin-modifying enzymes of the 2-oxoglutarate and iron(II)-dependent oxygenase superfamily HARVARD UNIVERSITY Anjana Rao TahilianiMamta VChromatin dynamics are critically influenced by the covalent modifications of both histone tails and DNA. Methylation of lysine residues in histone tails ...
K. Archer, "Chromatin-modifying enzymes as therapeutic targets: part 2," Expert Opinion on Therapeutic Targets, vol. 12, no. 11, pp. 1457-1467, 2008.Chromatin-modifying enzymes as therapeutic targets--Part 2. Keppler BR,Archer TK. Expert Opinion on Therapeutic Patents . 2008...
Whereas several proteins are known to regulate chromatin marks associated with the distinct epigenetic states of cells before and after reprogramming, the role of specific chromatin-modifying enzymes in reprogramming remains to be determined. To address how chromatin-modifying proteins influence reprogramming...
While several proteins are known to regulate chromatin marks associated with the distinct epigenetic states of cells before and after reprogramming2,3, the role of specific chromatin modifying enzymes in reprogramming remains to be determined. To address how chromatin-modifying proteins influence ...
Chromatin-modifying enzymesHistone methylationlncRNAHistone acetylationPCG TRXGLong-non-coding RNA (lncRNA) regulates gene expression through transcriptional and epigenetic regulation as well as alternative splicing in the nucleus. In addition, regulation is achieved at the levels of mRNA translation, ...
The discovery of enzymes that modify has revealed that transcription is an enzymically driven process. Such modifications can recruit specific and mediate changes that affect transcription either positively or negatively. Important biological pathways leading to are under the control of these enzymes, and...
Pack Size: 100 Reactions Quantity Or Email to Your Purchasing Agent Species:Human Source:SF9 cells Epitope Tag:6His-FLAG Mol Wgt:181 kDa Description Full length recombinant human SMARCA2 Remodeling Enzyme. SMARCA2 is a core ATPase subunit of the ATP-dependent chromati...
screening for compounds that modulate the activity of chromatin modifying enzymes, comprising contacting the compound with a cell comprising a polynucleotide encoding fusion proteins comprising zinc finger proteins and chromatin modifying enzymes anddetermining the difference in gene expression US 7785792 B2 ...
Molecular biology The transcriptional regulation of the pro-survival protein Grp78 by activating transcription factors and chromatin-modifying enzymes| Its upregulation in response to HDAC-inhibitor treatment and the therapeutic consequences UNIVERSITY OF SOUTHERN CALIFORNIA Amy S. Lee Baumeister Peter J DOI...
Temporal Recruitment of Transcription Factors and SWI/SNF Chromatin-Remodeling Enzymes during Adipogenic Induction of the Peroxisome Proliferator-Activated... The peroxisome proliferator-activated receptor gamma (PPARgamma) regulates adipogenesis, lipid metabolism, and glucose homeostasis, and roles have emerged...