Cairns BR: Chromatin remodeling complexes: strength in diversity, precision through specialization. Curr Opin Genet Dev 2005, 15:185-190. This is a comprehensive review on chromatin-remodelling complexes. Emphasis is placed on how ATPase subunits achieve their specialized functions, depending on the ...
The Biology of Chromatin Remodeling Complexes:染色质重塑复合物的生物学of,生物,物的,染色质重塑,The,the,生物学,染色质,染色质的 文档格式: .pdf 文档大小: 1.73M 文档页数: 35页 顶/踩数: 0/0 收藏人数: 1 评论次数: 0 文档热度: 文档分类: ...
The technique involves flash-freezing proteins at a speed where water molecules don't have time to re-organize to form crystalline ice. These protein complexes are then directly imaged by an electron microscope, and their shape can then be reconstructed in 3D through a supercomputing cluster. This...
Nucleosomes have long been known to inhibit DNA transactions on chromosomes and a remarkable abundance of multiprotein complexes that either enhance or relieve this inhibition have been described. Most is known about chromatinremodeling complexes that perturb nucleosome structure....
必应词典为您提供Chromatin-remodeling-complexes的释义,网络释义: 染色质重塑复合物;染色质重塑复合体;
WSTF knock down results in an accumulation of the ATPase CHD4, a component of the NuRD chromatin remodeling complex, which is responsible for establishing a repressive poised state at the promoter. The TTF-1, which binds and affect the binding of the chromatin complexes, is important to ...
Disordered chromatin remodeling regulation has emerged as an essential driving factor for cancers. Imitation switch (ISWI) family are evolutionarily conserved ATP-dependent chromatin remodeling complexes, which are essential for cellular survival and function through multiple genetic and epigenetic mechanisms. ...
Studies have identified direct interfacing with other cancer related protein complexes, SWI/SNF component loss in cancer cell lines and numerous human cancers, enhanced tumor development in animal knockout models, and References (20) J.M. Garcia-Pedrero et al. The SWI/SNF chromatin remodeling ...
a variety of chromatin remodeling factors use the energy of ATP hydrolysis to facilitate the interaction of proteins with nucleosomal DNA. ATP dependent chromatin remodeling complexes are characterized by the presence of an ATPase subunit from SNF2-like family of the DEAD/H (SF2) DNA-stimulated ATP...
Cancer-specific retargeting of BAF complexes by a prion-like domain Cell, 171 (2017), pp. 163-178 View in ScopusGoogle Scholar 69. G.J. Sandoval, et al. Binding of TMPRSS2-ERG to BAF chromatin remodeling complexes mediates prostate oncogenesis Mol. Cell, 71 (2018), pp. 554-566 View...