CHROMATIN-remodeling complexesHISTONE acetyltransferaseHISTONESCHROMATINTRANSGENIC organismsADENOSINE triphosphataseDNAOver the last 3 decades ATP-dependent chromatin remodelers have been thought to recognize c
One class of enzyme that has not generated much interest is the chromatin remodeling complexes. In this review, we will present evidence from the literature that these enzymes have both causal and enabling roles in the transition to advanced stage cancers; as such, they should be seriously ...
There is increasing evidence that ATP-dependent chromatin remodeling complexes based on the alternative DNA-dependent ATPases, Brg1 and Brm, plays essential roles during neural development in both vertebrates and invertebrates. This remodeling complex has dedicated functions at different stages of neural ...
However, we and other laboratories have characterized the complexes from non-transformed cells and find that www.cell-research.com | Cell Research npg ATP-dependent chromatin remodeling 402 the mammalian complexes are less similar to ySWI/SNF than we initially thought [120, 121, 124]. Recent ...
ATP-dependent chromatin remodeling complexes play crucial roles in various biological processes including enhancing local DNA accessibility, regulating gene transcription, and facilitating DNA replication and repair. Based on their functional structural domains, these complexes may be categorized into four famil...
ATP-dependent chromatin-remodeling complexes. Mol Cell Biol The importance of histones and chromatin structure in the regulation of eukaryotic gene transcription has become much more widely accepted over the past few years. It has been clear for a decade that histones contribute to the regulation.....
Chromatin-Remodeling Complex for Transactivation. Mol Cell Biol. 2003 (17):6210-6220. Narlikar GJ et al. Cooperation between complexes that regulate chromatin structure and transcription. Cell. 2002 108(4):475-87 Vignali M et al. ATP-dependent chromatin-remodeling complexes. Mol Cell Biol. 2000...
2. ATP-Dependent Chromatin Remodeling Complexes Specific gene expression programs, which depend largely on the organization of the associated chromatin, define a variety of cellular processes like differentiation, proliferation, and stemness [13]. ATP-dependent chromatin alterations, as one of the major...
to study the complexes upon chromatin templates with all of the histone modifications and complexity of the actual genomic sites where they carry out their functions. With these caveats, we will review what is known of the mechanism underlying the biologic actions of ATP-dependent chromatin ...
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