During DNA virus infection, HIRA influences chromatin remodeling, affecting both viral and host DNA accessibility, which impacts viral replication and gene expression. Additionally, the histone variant H3.3 is
R. Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics. Sci. Adv. 1, e1500447 (2015). Article PubMed PubMed Central CAS Google Scholar Cismasiu, V. B. et al. BCL11B functionally associates with the NuRD complex in T lymphocytes to ...
www.nature.com/scientificreports OPEN Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and received: 26 February 2016 accepted: 27 June 2016 Published: 18 July 2016 undergo pachytene chromatin inactivation? Sergey Matveevsky1, Irina Bakloushinskaya2 & Oxana ...
Where is DNA found in a cell, and how do we extract it? Describe the structure of DNA and how it complexes with proteins for packing. What is chromatin made of? Explain chromatin remodeling. What is it and what does it do to DNA?
Chromatin assembly and disassembly are highly orchestrated processes that are coordinated by histone chaperones and ATP- dependent chromatin remodeling complexes (Figure 1) [5]. Histone chaperones promote chromatin assembly by preventing non-specific histone-DNA interactions while also promoting the correct ...
lncRNA 5430416N02Rik promotes the proliferation of mouse embryonic stem cells by activat- ing Mid1 expression through 3D chromatin architecture. Stem Cell Rep. 2020;14(3):493–505. 42. Zhang N, Hu X, He S, Ding W, Wang F, Zhao Y, et al. LncRNA MSC-AS1 promotes osteogenic ...
targeting or function of some of the proteins acting downstream of HJURP to effectively incorporate CENP-A might require condensin II. Among those proteins could be remodeling complexes like FACT, RSF1 or CHD1 [34,35] or some of the components of the constitutive centromere-associated network (...
These epigenetic changes entail post-synthetic modifications of DNA nucleotides or associated histone proteins (See Box 1), as well as nucleosome remodeling and substitution of histone variants, which, amongst others, inflect the topology of the chromatin landscape, alter the accessibility of ...
It has a crucial role in the mechanical connection between the actin flow and cell adhesion complexes during cell migration. Nematic order Refers to a state of molecular alignment observed in cellular populations such as fibroblasts, akin to the alignment seen in liquid crystals. In this state, ...
Germ cells are the only cells in the body capable of giving rise to a new organism, and this totipotency hinges on their ability to assemble membraneless germ granules. These specialized RNA and protein complexes are hallmarks of germ cells throughout th