Kyle has taught college level biology and helped with middle-school science programs. Have you ever wondered how or why the cells of our body store information? Many of us know that the molecule DNA contains all the information that makes us who we are. After this lesson you will be able...
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
Loss-of-function Aspergillus nidulans CclA, a Bre2 ortholog involved in histone H3 lysine 4 methylation, activated the expression of cryptic secondary metabolite clusters in A. nidulans. One new cluster generated monodictyphenone, emodin and emodin deriv
Then, we used the ChromHMM OverlapEnrichment function to calculate the overlap fold enrichment between each human state (liftedOver to mm10) and each mouse state. For each pair of human-mouse states, we determined whether the pair of states correspond to a one-to-one mapping by checking ...
on certain “excesses” and keep fit (in both body and mind) to maintain a healthy aging process. Now, a team of fitness enthusiasts has revealed that long-term treatment with the diabetes drug metformin maintains an aging population of monkeys “in form,” including at the epigenetic level!
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
To investigate the effects of upon structure and function, we studied the assembly and properties of that contains unmodified recombinant core . To this end, we synthesized the core in . The purified were lacking covalent modifications as well as their N-terminal initiating . The recombinant were...
Three-dimensional (3D) chromatin structure is closely related to genome function, in particular transcription. However, the folding path of the chromatin fiber in the interphase nucleus is unknown. Here, we systematically measured the 3D physical distance between pairwise labeled genomic positions in ...
1、Chapter 7,Chromosomes, chromatin, and the nucleosome,Molecular Biology of the Gene - James Watson et al.,Part I: Chemistry and Genetics Part II: Maintenance of the Genome Part III: Expression of the Genome Part IV: Regulation Part V: Methods,Ch 6: The structures of DNA and RNA Ch 7...
The relationships between chromosomal compartmentalization, chromatin state and function are poorly understood. Here by profiling long-range contact frequencies in HCT116 colon cancer cells, we distinguish three silent chromatin states, comprising two ty