Results We report the novel observation that prion infection altered the membrane composition and significantly increased total cholesterol levels in two neuronal cell lines (ScGT1 and ScN2a cells). There was a significant correlation between the concentration of free cholesterol in ScGT1 cells and ...
As an essential structural component of eukaryotic cell membranes1,2, cholesterol is typically absent from bacterial cell membranes3. By leveraging on this difference, bacterial cells manage to evolve cholesterol-dependent cytolysins (CDCs), a family of bacterial protein toxins that form circular memb...
Cholesterol levels inversely reflect the thermal sensitivity of mammalian cells in culture 来自 NCBI 喜欢 0 阅读量: 22 作者:AE Cress,EW Gerner 摘要: Cholesterol is a primary component of the mammalian cell plasma membrane. Although its function is unknown, it may be of major importance in ...
The almost white hairs of the Werner's syndrome patient displayed low levels of CHSU, possibly indicating a precarious hair stability. A small but statistically significant linear correlation between donor age and integral CH in hair (n=51; y=97.7+0.9x; cc=0.32; p<0.05) was detected. No ...
In both cases, direct manipulation of cholesterol levels elucidates that a graphene-induced cholesterol increase underlies the observed potentiation of each cell signaling pathway. These findings identify cholesterol as a mediator of graphene’s cellular effects, providing insight into the biological impact...
One is the study of the net rate at which the cholesterol-rich lipoprotein LDL transfers from blood plasma into the wall of the artery; this can be measured in surgical patients using labeled lipoprotein. This rate decreases with decreasing levels of LDL in plasma; by extrapolation to zero ...
Correlations of elevated levels of hexacosanoate in erythrocyte membranes with risk factors for atherosclerosis We analyzed erythrocyte membrane C26:0 from 504 volunteers by high-performance liquid chromatography. The associations between the elevated levels of eryth... Y Antoku,K Tsukamoto,Y Miyoshi,...
The team also studied mice lacking one of the three Asters, and confirmed that it is required for HDL movement from the cell membrane into the endoplasmic reticulum in the adrenal gland, which uses cholesterol to make steroid hormones such as cortisol. ...
cell membrane is approximately one order of magnitude less permeable to cisplatin in comparison to the membrane of the normal cell. We discuss possible reasons for this difference in details and compare obtained results with available experimental data. We use the ISD methodology to compare ...
3). Longer incubation times with MβCD (that is, 240 min) did not result in higher levels of A2AR specific binding (469.7±13.7 fmol per mg protein, n=2), likely due to a compensatory mechanism to maintain cholesterol homeostasis in treated cells. Saturation binding experiments using...