(LL37/DNA, TLR-9 ligand)21. Transcriptional profiles were generated using Affymetrix microarrays in the conditions 0, X, Y and X+Y, at one or two time points for each pair of signals, in order to get a multiparametric assessment of output responses to combined stimuli. Quality control of...
Neural Control of BehaviorHORN, G. Behavioral and cellular responses to novel and repeated stimuli. In: The NeuraZ Control of Behavior, edited by R. E. Whalen, R. F. Thompson, M. Verzeano, and N. M. Wein- berger. New York: Academic, 1970, p. 103-127....
It was concluded that neither RNA nor protein synthesis is required for some, if not all, the early responses to growth stimuli measured here. The inhibited cell appears to be a poised system which carries out a programmed array of reactions characteristic of the cell type following perturbation...
In order to unveil the multi-layered temporal gene responses in these processes, we measure gene expression in IL-6 stimulated mouse hepatocytes by a time-course microarray experiment. Applying GraDe with a literature based gene regulatory network, we are able to infer associated biological processes...
The technological revolution in biological research, and in particular the use of molecular fluorescent labels, has allowed investigation of heterogeneity of cellular responses to stimuli on the single cell level. Computational, theoretical, and synthetic biology advances have allowed predicting and manipulat...
AS plays a decisive role in generating protein diversity, regulating development and growth, and controlling responses to stimuli36,37. To determine whether AS is induced in BHK-VECs and plays a role in their resistance to FMDV infection, we investigated differences in splicing patterns between ...
The implications of these changes in connection with the cellular responses after different doses of ionizing radi. . . 分析了这些变化在不同剂量电离辐射所致细胞反应发生中的意义。 www.chemyq.com 2. These protein phosphorylation cascades link extracellular stimuli to a wide range of cellular responses...
We show that cellular collagen production can be readily detected and used to assess cellular stress responses to a variety of external stimuli, including exposure to nanoparticles. Results of the study showed a 20% and 95% reduction of collagen production following 4 hour exposure to 10 μg ...
Integration of cell signals in both rapid time and small space, and importantly, between different cell populations (communication and systems modeling) will permit many more valuable measurements of the dynamic aspects of cell responses to various chosen stimuli and their feedback. This represents ...
Although many cellular computations involving binary “yes/no” decisions may be interpreted as digital computations, and digital logic computations are certainly suited to applications such as biosensors, cells often exhibit graded responses to stimuli that are more appropriately viewed as analogue computat...