In particular, the compounds of Formula (I), lower elevated levels of unsaturated, non-arachidonate phosphatidic acid (PA) and diacylglycerol (DAG) derived from said PA within seconds of the primary stimulus and their contact with said cells. The modulatory effect depends on the nature of the ...
MODULATION OF CELLULAR RESPONSE TO EXTERNAL STIMULIMODULATION OF CELLULAR RESPONSE TO EXTERNAL STIMULICompounds of formula (I), wherein one and only one of R?1 and R?3 is a straight-chain or branched-chain $g(v)- or ($g(v)-1)-hydroxyalkyl (5-8C), or is an ($g(v)-1)-oxoalkyl...
The genes up-regulated after TCS treatment among Endos, with respect to the expression in control group, were found to be involved in cellular response to external stimulus, the canonical Wnt signaling pathway, response to hypoxia and fibroblast proliferation (Additional file 1: Fig. S7), ...
This, in concordance with the lack of orthologous genes to the PYL/PYR/RCAR Nature Communications | (2024)15:5988 2 Article https://doi.org/10.1038/s41467-024-49844-3 a -log10 FDR enrichment 012345 Treatment NaCl Mannitol Cellular response to external stimulus Cellular response to abiotic ...
different responses of a cell to an external stimulus. Figure 1 GraDe: Graph-decorrelation algorithm. In cells, various biological processes are taking place simultaneously. Each of these processes has its own characteristic gene expression pattern, but different processes may overlap. A cell's total...
The nanosensor can be used to study cellular reactions and cytotoxicity an order of magnitude faster and using 100-fold smaller volume of reagents when compared to conventional analyses: this methodology allows monitoring the response to external stimuli in the order of hours, i.e. way before ...
“cellular response to growth factor stimulus” in ECTOs (Fig.2C). To further characterize the pluripotency stage of bovine embryonic development, we analyzed the activity of signaling pathways related to pluripotency during epiblast development. We observed a downregulation of genes related to the ...
"Cellular Assays" orCell-based Assaysare essential tools for studying cellular mechanisms in live cells. Many cellular assays are configured for identifying or quantifying a specific response to an external stimulus (e.g. replication, division, or metabolic activity). Other assays measure cellular hea...
Light is considered as an external stimulus to plant cells. The photosynthetic light response is an important process that allows plants to optimize the efficiency ofphotosynthesis, which is the core technology for green energy. However, currently, little is known about the molecular mechanisms behind...
[43]. HSP90 comes in two isoforms: the inducible HSP90α and the constitutive HSP90β. While HSP90β, but not HSP90α, is critical for the cell viability, HSP90α is mainly involved in cell responses to external stressors. Of note, cancer cells predominantly secrete the HSP90α isoform...