Based on previous reports39,40, genes related to pattern recognition receptors, antimicrobial peptides, complement molecules, lectin family members, cytokines in innate immunity, interleukin-1 family members and receptors, tumor necrosis factor, chemokines, and the major histocompatibility complex were ...
Thus, to verify if different mycotoxins, either alone or in combination, could specifically damage cartilage, and to obtain more evidence about the relationship between mycotoxins and KBD prevalence, we compared the potential of T-2 toxin and/or DON to cause toxicity in cartilage, as well as he...
A number of mRNA expressions of interleukin-12 and interferon (IFN)-as immune cell activating cytokines, perforin and granulysin as cytotoxic factors, and myxovirus resistance protein (MX)-1 and MX-2 as anti-virus factors of PBMC were analyzed after culturing cells with phytohemagglutinin (PHA)...
MLNC from infected BALB/K mice produced elevated levels of the Th2-specific cytokines interleukin-5 (IL-5) and IL-9. IL-3 and IL-4 remained at or just above normal. Interferon-gamma (IFN-gamma) (a Th1-type cytokine) was secreted only in small amounts. MLNC from infected sus...
stressresponse mediated bycortisol,catecholamines, and interleukins 6 and 2,protein degradationcan occur with release of amino acids. All amino acids may be catabolized to either AcCoA or some Krebs cycle intermediate. Accordingly, amino acids can be mobilized for energy production as well as de ...
Key elements of the SASP are the proinflammatory cytokines interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-1(IL-1)「 IL-1is considered one of the master regulators of the SASP 」 in OIS: chemokines binding to the IL-8 receptor C-X-C motif chemokine receptor 2...
摘要:Interleukin-37 (IL-37) is an inhibitory member of the IL-1 family of cytokines. We previously found that balanced selection maintains common variations of the human IL37 gene. However, the functional consequences of this selection have yet to be validated. Here, using cells expressing e...
Key elements of the SASP are the proinflammatory cytokines interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-1(IL-1)「 IL-1is considered one of the master regulators of the SASP 」 in OIS: chemokines binding to the IL-8 receptor C-X-C motif chemokine receptor 2...
Serum tumor necrosis factor and interleukin 1 in leprosy and during lepra reactions. Tumor necrosis factor—α (TNF), one of the mediators of septic shock, has a role in the immunopathological complications of several infections. However, its role in leprosy is yet unclear. In this study, ser...
The interleukin-4 receptor: signal transduction by a hematopoietin receptor Over the last several years, the receptors for numerous cytokines have been molecularly characterized. Analysis of their amino acid sequences shows that so... AD Keegan,JH Pierce - 《Journal of Leucocyte Biology》 被引量...