Active tumor cell motility has long been appreciated to play a major role in invasion and metastasis. Tumor cells exhibit an amoeboid movement similar to that of polymorphonuclear (PMN) leukocytes and the lower eukaryote Dictyostelium , characterized by pseudopod protrusion at the leading edge of ...
The process during embryogenesis whereby the embryo is transformed from a hollow sphere of cells into a structure with three germ layers: ectoderm, mesoderm and endoderm. Lamella The flattened region immediately behind the lamellipodium. Glu-tubulin (Also known as detyrosinated tubulin). A post-...
5.Structure&FunctionsofplasmamembraneOutline ☆§1molecularstructureofPM§2cellsurface ☆§3transmembranetransport (自学)§4,5,6 细胞识别、信号传导、膜抗原 §7cellmembrane&medicine Outline •cellmembrane=plasmamembrane(质膜).•Biomembrane生物膜:allmembranesof cell.•Allmembranesareunitmembrane.•...
anionic but not cationic surfaces promoted two modes of pseudopod formation by HCS-2/8 cells, in a random progression and as a “cell recognition signal”. This phenomenon was associated with a cellular mechanism to optimize the anchoring process. Interestingly, cells developed pseudopods on cation...
Perhaps, macropinocytosis is an in vitro activity which simply reflects an inherent capability to generate the pseudopod extensions that engulf phagocytic ligands. There are several similarities between phagocytosis and macropinocytosis. Both are dependent on remodeling of the actin cytoskeleton and cdc42 ...
Plant roots perceive heat stress (HS) and adapt their architecture accordingly, which in turn influence the yield in crops. Investigating their heterogeneity and cell type-specific response to HS is essential for improving crop resilience. Here, we gener
(e) The bar graph showing that there is no significant difference in the length of pseudopodia between the motile spe-8(lf) sperm and non-motile spe-8(lf) sperm. Each dot represents the length of one pseudopod. 176 sperm with poor motility and 181 sperm with normal motility were ...
These specialized structures enable tumour cells to penetrate the extracellular matrix by extending filamentous pseudopod-like projections facilitated by membrane-associated protein hydrolases [4, 5]. Subsequently, these invasive cells enter the circulatory system, forming metastatic foci through colonization ...
forms amoeba pseudopod forms cleavage the separates cells in mitosis characteristics of intermediate filaments coil proteins keratin maintains cells shape characteristics of microtubules made of tubulin hollow support motility forms spindle during mitosis ...
based on MD cell-specific surface labeling with anti-Lrp1b (green), and intracellular vesicular labeling with anti-Ccn1 (red) antibodies. Human MD cells also feature numerous, long basal nanotubes (FIG. 23C), and highly dynamic pseudopod formation (motility) that causes spontaneous self-aggregat...