To assess the potential impact of CR cell death in the development of the cortical circuit, we first aimed to identify the circuit that CRs are part of. To achieve this in a comprehensive and unbiased manner, we utilized compound mouse genetics in combination with pseudo-typed rabies viral tra...
The trajectories of cell movement depend on the size, rhythm, and direction of long series of pseudopods. These pseudopod properties are regulated by internal factors such as memory of previous directions and by external factors such as gradients of chemoattractants or electric currents. Here a ...
anionic but not cationic surfaces promoted two modes of pseudopod formation by HCS-2/8 cells, in a random progression and as a “cell recognition signal”. This phenomenon was associated with a cellular mechanism to optimize the anchoring process. Interestingly, cells developed pseudopods on cation...
We stored the coordinates of each node and we assigned a type to each node, depending on whether the node fell inside a pseudopod, the initial cell, or the veins. After constructing the graph, a subroutine calculated the connectivity of each node, and simplified the graph in order to avoid...
and new blebs were continuously generated (Movie S1), so kymographs fromscarknockout cells have a stepped appearance (Figure 3B). Wild-type SCAR (WT) rescues normal pseudopod progression (Figure 3A;Movie S2), giving kymographs with smooth runs interspersed with steps when the leading edge spli...
C Representative examples of targets from each class. Normalized expression values in cells with targeting gRNAs (red) versus NT controls (gray) are shown. The title of the plot indicates the gene plotted. D Plot depicting the effect of gene expression levels on our ability to detect ...
Extracellular lipid-mediated signaling in tumor-cell activation and pseudopod protrusion Extracellular lipid-mediated signaling in tumor cell activation and pseudopod protrusion. Int J Cancer 2000;88:593-600. [PubMed: 11058876]... L Hodgson,EC Kohn,C Dong - 《International Journal of Cancer》 被...
Rac1 Drives Melanoblast Organization during Mouse Development by Orchestrating Pseudopod-Driven Motility and Cell-Cycle Progression Li A, Ma Y, Yu X, et al: Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod-driven motility and cell-cycle progression. Dev Cell ...
Animals to be administrated with CAR-T were intravenously dosed with 0.2 mL Raji cells (3 ~ 5 × 105 cells per animal) for tumor xenografts in advance. If a Raji cell with fluorescence reporter was used, the fluorescence intensity of animals for the proliferation of the lymphoma could be de...
Some examples are the bulbous lobopodia used by the parasitic amoeba Entamoeba histolytica and the broad, flat lamellipodia produced by the amoeba Acanthamoeba castellani.1 Mammalian cells also exhibit pseudopods of the lamellipodia variety along with accompanying microspikes that are fine hair-like ...