The trajectories of cell movement depend on the size, rhythm, and direction of long series of pseudopods. These pseudopod properties are regulated by internal factors such as memory of previous directions and by external factors such as gradients of chemoattractants or electric currents. Here a ...
anionic but not cationic surfaces promoted two modes of pseudopod formation by HCS-2/8 cells, in a random progression and as a “cell recognition signal”. This phenomenon was associated with a cellular mechanism to optimize the anchoring process. Interestingly, cells developed pseudopods on cation...
Under confocal laser scanning microscopy they also show alone pseudopod-like basal process approximately 50–70 µm long, extending from these cells and form an interface between the mucosal epithelium and the lamina propria. These processes resembling a synapse appear to interact with neighboring ...
We stored the coordinates of each node and we assigned a type to each node, depending on whether the node fell inside a pseudopod, the initial cell, or the veins. After constructing the graph, a subroutine calculated the connectivity of each node, and simplified the graph in order to avoid...
PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis. J. Cell Sci. 120, 2517–2531 (2007). CAS PubMed Google Scholar Lee, T. & Montell, D. J. Multiple Ras signals pattern the Drosophila ovarian follicle cells. Dev. Biol. 185,...
Drug targets with genetic evidence are expected to increase clinical success by at least twofold. Yet, translating disease-associated genetic variants into functional knowledge remains a fundamental challenge of drug discovery. A key issue is that the va
Extracellular lipid-mediated signaling in tumor-cell activation and pseudopod protrusion Extracellular lipid-mediated signaling in tumor cell activation and pseudopod protrusion. Int J Cancer 2000;88:593-600. [PubMed: 11058876]... L Hodgson,EC Kohn,C Dong - 《International Journal of Cancer》 被...
Data are normalized by the number of double-positive cells for three independent experiments (D) CD99 with UCHL1 and (E) PODXL2 with c-KIT Full size image Discussion Mammalian spermatogenesis is a complicated and dynamic cellular differentiation process. Gene expression profiles of male germ ...
and new blebs were continuously generated (Movie S1), so kymographs fromscarknockout cells have a stepped appearance (Figure 3B). Wild-type SCAR (WT) rescues normal pseudopod progression (Figure 3A;Movie S2), giving kymographs with smooth runs interspersed with steps when the leading edge spli...
Moreover, recent studies indicated the influence of EECs on neighboring cells or neurons via long pseudopod-like basal processes called ‘neuropods’. The terminal end of these neuropods, frequently resembling a synapse, probably connects with epithelial cells or intestinal neurons [53], thereby ...