网络周期特异性药物;细胞周期特异性药物 网络释义
【答案】：细胞周期特异性药物：是指只对增殖周期某些时相的细胞敏感的抗恶性肿瘤药。如抗代谢药只对S期细胞敏感，长春碱类药物只对M期细胞敏感。
细胞周期特异性药物(cellcyclespecificagents,CCSA) 正确答案:仅对增殖周期的某些时相敏感而对G0期细胞不敏感的药物。往往作用较弱。如抗代谢药物、长春碱类药物。 点击查看答案
细胞周期特异性药物(cell cycle specific agents,CCSA)是指那些能作用于细胞增殖的整个或大部分周期时相的药物。由于S期是DNA合成的主要时期,M期是细胞分裂的主要时期,因此大多数CCSA都针对于这两个时期,可分为:①S期特异性药物,作用机制为抑制DNA合成,抑制拓扑异构酶的药物;②G2期特异性药物,主要为破坏DNA结构(在...
【答案】：细胞周期非特异性药物：是指能够杀灭处于增殖周期各时相的细胞甚至G0期细胞的抗恶性肿瘤药。如烷化剂、抗肿瘤抗生素和铂类抗肿瘤药物。
更多“细胞周期特异性药物(cell cycle specific agents)”相关的问题 第1题 皮瓣移植的术后并发症包括() A.皮瓣血运障碍 B. 皮瓣感染 C. 皮瓣下血肿、血清肿 D. 缝合缘瘢痕增生 点击查看答案 第2题 皮瓣移植的术后并发症包括() A.皮瓣血运障碍 B.皮瓣感染 C.皮瓣下血肿、血清肿 D.缝合缘瘢痕增生 点击...
The study of cell-cycle control in plants presents two major opportunities. First, one can learn about the general cell-cycle machinery. This has the potential not only to reveal new, plant-specific control mechanisms but also to contribute to the understanding of canonical cell-cycle regulation ...
A particular form of apoptosis that occurs during mitosis as a result of aberrant chromosome segregation or DNA damage, typically related to inactivation of cell cycle checkpoints. Synthetic lethality With regard to cancer therapy, this concept postulates that inhibition of a specific protein is lethal...
Therefore, while little is known about cell cycle-specific substrates, it is likely that RIPK3 has other functions of its kinase activity outside of necroptosis. Among the more recently identified substrates of RIPK3 is the autophagy protein ULK1, which regulates both canonical and alternative ...
(Rb), inhibiting the activation of the E2F genes, and resulting in cell cycle exit. However, it is worth mentioning that p21 can also be activated in a p53-independent manner[25]. p16, currently recognized as one of the most specific senescence markers, directly interacts and inhibits the ...