H2 possesses the pyroptosis-inducing capacity and contains a number of enterotoxins including cytotoxin K (CytK). In the present work, we examined the cytotoxicity of the CytK of H2 to human macrophages. CytK bound macrophages by interaction with the plasma membrane and caused cellular structure ...
There is no information on cytokine profiles for use as markers of protection in Campylobacter jejuni infection. To study this, we used outer membrane protein (MOMP [PorA]) as the vaccine for protection and spleen cell cytokines as markers of protection.
The cytotoxin may be attached to, or included in, either the MHC molecule or the peptide which will be presented to a patient's T-cells bound as a pMHC so that the cytotoxin (e.g. radionuclide or positron emitter) will inflict lethal damage to the specifically binding T-cell. The ...