Expression of EIN3 transcription factor; Influence of ubiquitin/proteasome pathway in rapid protein degradation; Role of EIN3-binding F-box protein 1 and 2 in ethylene response.doi:10.1038/nrm1323NoneNature Reviews Molecular Cell BiologyCroager E. Plant cell biology - Protein degradation protects ...
M. PROTAC targeted protein degraders: the past is prologue. Nat. Rev. Drug Discov. 21, 181–200 (2022). Article CAS PubMed PubMed Central Google Scholar Wu, T. et al. Targeted protein degradation as a powerful research tool in basic biology and drug target discovery. Nat. Struct. ...
20220223-Cell Biology-Golgi and lysosome and protein degradation是细胞生物学的第6集视频,该合集共计16集,视频收藏或关注UP主,及时了解更多相关视频内容。
nature cell biology letters articleLetter Published: 21 September 2020 Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions Longyong Xu, Xia Liu, Fanglue Peng, Weijie Zhang, Liting Zheng, Yao Ding, Tian...
The importance of protein degradation in the ER during leptin signaling has been unclear. Here, the authors show that SEL1L-HRD1 ER-associated degradation modulates leptin signaling in POMC neurons by degrading misfolded leptin receptors in the ER. Hancheng Mao , Geun Hyang Kim & Ling Qi Artic...
2022年4月25日,来自德国马克斯普朗克生物化学研究所的Reinhard Fässler教授团队在Nature Cell Biology上发表了题为CDK1–cyclin-B1-induced kindlin degradation drives focal adhesion disassembly at mitotic entry的论文。该研究结合磷酸化,...
Nature Cell Biology volume 21, pages 1382–1392 (2019)Cite this article 6198 Accesses 26 Altmetric Metrics details Abstract In the unicellular eukaryote Saccharomyces cerevisiae, Cln3–cyclin-dependent kinase activity enables Start, the irreversible commitment to the cell division cycle. However, the ...
both in cultured cells and mouse liver or expression of CMA-resistant PLINs leads to reduced association of ATGL and macrolipophagy-related proteins with LDs and the subsequent decrease in lipid oxidation and accumulation of LDs. We propose a role for CMA in LD biology and in the maintenance ...
from Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, reported their astonishing discoveries on structure and degradation of the back splicing-derived circRNAs regulate PKR activation in innate immunity (Cell 177, 2019). In this report, the authors found that stimulatio...
近日，来自德国慕尼黑大学基因中心的Julian Stingele 研究团队和英国癌症中心的Stephen P. Jackson研究团队合作在Nature Cell Biology杂志上发表题为Transcription-coupled repair ofDNA–protein cross-links depends on CSA and CSB的研究论文，该研究发现了CSA和CSB（ Cockayne syndrome (CS) proteins）在介导DNA -...