然而,CD8+ T 细胞活化染色质三维结构变化以及调控三维染色质结构促进 CD8+ T 细胞活化的机制仍未被系统和深入地研究。 2025 年 1 月 16 日,董晨教授团队在Nature Communications期刊发表了题为:TRIM28 is an essential regulator of three-dimensional chromatin state underpinning CD8 + T cell activation 的研究论...
董晨教授团队在《Nature Communications》期刊上发表了一篇题为“TRIM28 is an essential regulator of three-dimensional chromatin state underpinning CD8+ T cell activation”的研究论文。该研究揭示了TRIM28在CD8+ T细胞活化过程中三维染色质状态的关键调控作用,为理解CD8+ T细胞的免疫活化机制提供了新的视角,并为开...
Were cultured in a medium by separating CD8 T cells, were added cytokines, including IL-4 GM-CSF, IFN-gamma, TNF-alpha, Lectin, and IL-2,, the present invention, CD8 T in vitro relates to a composition for preventing or treating viral infections diseases, including CD8 T cells activated...
(2016). Mitochondrial biogenesis and proteome remodeling promote one-carbon metabolism for T cell activation. Cell Metab. 24, 104–117.3. Gilissen, J., Jouret, F., Pirotte, B., and Hanson, J. (2016). Insight ...
2024年8月28日,中国医学科学院、北京协和医学院医药生物技术研究所李珂团队(博士研究生刘莹和博士后王凤为论文共同第一作者)在Science Translational Medicine期刊发表了题为:Activation and antitumor immunity of CD8+ T cells are supported by the glucose transporter GLUT10 and disrupted by lactic acid 的研究论文...
英文题目:Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer 中文题目:谷氨酰胺酶抑制损害 STK11-/Lkb1 缺陷型肺癌中 CD8 T 细胞的活化 期刊:Cell Metabolism IF:27.287 DOI:https://doi.org/10.1016/j.cmet.2022.04.003 ...
MSS CRC CD8+ T cells主要标记contradictory inflammatory markers, i.e., immuno-regulation (PD-131), suppressor of T cell activity (CD3886), T cell activation (CD28, CD4487,88) and unconventional T cells (NKp4689)。 总之,观察到 MSI CRC CD8+ T 细胞暴露更多效应记忆样表面标记,而 MSS CRC ...
naive CD8+T是一个新手，很新的那种，它还没有修炼作为杀手要用到的一系列技能。致敏，其实就是告诉...
Discusses research being done on T cell-dendritic cell (DC) interaction. Reference to a study by F. Castellino et al, published in the 2006 issue of "Nature"; Hypothesis that CD8+ T cells are recruited to DC that are activated by CD4+ T cells; Role of chemokines in the recruitment of...
CD8+ T-cell Activation in Mice Injected with a Plasmid DNA Vaccine Encoding AMA-1 of the Reemerging Korean Plasmodium vivax 2011. CD8 T-cell activation in mice injected with a plasmid DNA vaccine encoding AMA-1 of the reemerging Korean Plasmodium vivax . Korean J. Parasitol... HJ Kim,BK...