Summary Top of page Summary Introduction Materials and method Results Discussion Acknowledgements References Because of the paucity of plasma HIV RNA viral load (VL) tests in resource-poor settings, the CD4 + T cell count is often used as the sole laboratory marker to evaluate the effectiveness ...
分泌性marker:IL-10+、IL-35+ 参考文献 Liet al.,Science376, eabi9591(2022). DOI: 10.1126/science.abi959 Cantor, H.; Shen, F.W.; Boyse, E.A. Separation of helper T cells from suppressor T cells expressing different Ly components. II. Activation by antigen: After immunization, antigen-s...
fig4e-h: 表面marker的差异富集分析显示MSI CRC CD8+ T cells 主要exposed markers of memory phenotype (CD12781), effector memory or polyclonal TCR phenotype (CD2582), immunoregulation (PDL183), T cell activation (CD5684), and cytokine signaling (CD12385)。MSS CRC CD8+ T cells主要标记contradictor...
Each symbol represents an individualmouse, *p=0.019 (CD4 Tconv), *p=0.011(CD8 T cells). Lower right panel: Heat map with markerexpression of the main T cell subsets. c t-SNE visualizationof markers on CD8 TCRβ cells. d Upperpanel: t-SNE plots of the main CD8 T cell subsets ...
Eosinophils deficiency enhances CD8+T cell apoptosis and decreases mouse survival upon infection.a,bStatistical analysis of the percentages and the counts of splenic CD8+T cells (a) and eosinophils (b) in WT mice during the early stage ofL.m. infection.cActivation state of splenic eosinophils as...
CD8+ T cells are essential in the defence against viruses. Recently, peptide–HLA class I tetramers have been used to study immune responses to viruses in humans. This approach has indicated consecutive stages of human CD8+ T-cell development in acute vi
We have recently shown extensive sequence and conformational homology between tumor-associated antigens (TAAs) and antigens derived from microorganisms (MoAs). The present study aimed to assess the breadth of T-cell recognition specific to MoAs and the c
Lower right panel: Heat map with markerexpression of the main T cell subsets. c t-SNE visualizationof markers on CD8+ TCRβ+ cells. d Upperpanel: t-SNE plots of the main CD8+ T cell subsets identifiedby FlowSOM algorithm. Lower panel: frequency of the main CD8+ Tsubsets identified by...
Dendritic cell-induced memory T cell activation in nonlymphoid tissues Science, 319 (2008), pp. 198-202 CrossrefView in ScopusGoogle Scholar Zhao et al., 2018 Y. Zhao, W. Zou, J. Du, Y. Zhao The origins and homeostasis of monocytes and tissue-resident macrophages in physiological situatio...
Rather, during initial T cell activation during both acute and chronic infection, these pathways are upregulated; yet, at these early time points, T cells are functional. It is possible that early during infection signals from positive costimulatory pathways outweigh those from negative pathways. ...