Human ↑=Upregulated ↓=Downregulated ○=Key marker ●=Subset 人全血10色免疫表型分析 鉴别多种T细胞亚群和髓细胞 抗体组合 人全血13色免疫表型分析 B细胞、T细胞亚群、NK细胞和髓系细胞免疫表型分析 抗体组合
Fig. 1. Inducible genetic deletion of Cd8a disrupts the homeostasis ofmemory and naive CD8+ T cells in the periphery. Fig2A-D,FigS7除了细胞数量的变化,CD8的敲除也影响了细胞表型。与对照组相比,CD8敲除组细胞的T细胞活化marker CD69和Fas表达上调,memory marker CD127和CD122表达下调,并且有更多的Naïv...
ARTICLES Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin Andrew M Intlekofer1, Naofumi Takemoto1, E John Wherry4,8, Sarah A Longworth1, John T Northrup1, Vikram R Palanivel1, Alan C Mullen1, Christopher R Gasink1, Susan M Kaech4,8, Joseph D Miller4, ...
Mouse ↑=Upregulated ↓=Downregulated ○=Key marker ●=Subset 小鼠脾细胞10色免疫表型分析 抗体组合
CD8+ central memory T cells (CD8+ TCM cells). CD8+ memory T cells with a high degree of proliferative potential upon reactivation, commonly identified by the expression of lymphoid homing marker CD62L, and that can be abundantly found in the spleen, blood and lymph nodes. CD8+ effector mem...
Transfer of CD8 + T cell memory using Bcl-2 as a marker . J Immunol 190 :940–947. doi:.10.4049/jimmunol.1103481 [ Cross Ref ]Dunkle A, Dzhagalov I, Gordy C, & He YW (2013) Transfer of CD8+ T cell memory using Bcl-2 as a marker. J Immunol 190(3):940-947....
小鼠的 CD8 T Cell Markers ↑=Upregulated ↓=Downregulated ○=Key marker ●=Subset 小鼠脾细胞10色免疫表型分析 抗体组合
小鼠的 CD8 T Cell Markers ↑=Upregulated ↓=Downregulated ○=Key marker ●=Subset 小鼠脾细胞10色免疫表型分析 抗体组合
fig4e-h: 表面marker的差异富集分析显示MSI CRC CD8+ T cells 主要exposed markers of memory phenotype (CD12781), effector memory or polyclonal TCR phenotype (CD2582), immunoregulation (PDL183), T cell activation (CD5684), and cytokine signaling (CD12385)。MSS CRC CD8+ T cells主要标记contradictor...
Thus, both the urea and citrulline cycles are employed by CD8+ T cells to clear ammonia and enable memory development. This ammonia clearance machinery might be targeted to improve T cell-based cancer immunotherapies. 结果...