Here, we show that when CD74 is overexpressed in human cancer and noncancerous epithelial cells, it interacts and interferes with the function of Scribble, a product of a well-known tumor suppressor gene. Furthermore, using ...
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Subsequently, the TIMER database was used to determine whether CD74 expression in liver cancer was related to the level of immune cell infiltration. The data indicated that the CNV of CD74 was notably related to the infiltration levels of CD4+ T cells, macrophages and neutrophils, and high am...
The G2032R missense mutation has been observed in patients with crizotinib-resistant non-small cell lung cancer harboring CD74-ROS1 rearrangement. Independent in vitro studies have confirmed that this mutation confers marked resistance to crizotinib cells over CD74-ROS1 alone. Multiple groups have ...
Microsatellite instability-high (MSI-H) metastatic colorectal cancer (CRC) patients are the dominant population in immune checkpoint blockade treatments, w
近日,求臻医学与福建省莆田市第一医院肿瘤内科黄伟明主任合作,首次报道了一例CD74-ROS1融合突变的恶性胸膜间皮瘤患者经克唑替尼治疗后达到持久性完全缓解。目前该案例报道(case report)已在线发表于Journal of Cancer Research and Clinical Oncology(IF:4.553)。
抗原抗体价格:价格电议产品详情:英文名称 Anti-CA125中文名称卵巢癌抗原抗体别 名 CA 125; CA125; CA-125; CA125 ovarian cancer antigen; Cancer antigen 125; ... 纯度:详见说明书% 包装规格:0.1ml/100μg0.2ml/200μg 1ml/1mg 用途:产品仅用于科研实验 ...
Subsequently, the TIMER database was used to determine whether CD74 expression in liver cancer was related to the level of immune cell infiltration. The data indicated that the CNV of CD74 was notably related to the infiltration levels of CD4+ T cells, macrophages and neutrophils, and high am...
Here, we show that when CD74 is overexpressed in human cancer and noncancerous epithelial cells, it interacts and interferes with the function of Scribble, a product of a well-known tumor suppressor gene. Furthermore, using epithelial cell lines expressing CD74 under the control of tetracycline...
of B-cells[136]. CD74 is also a high-affinity receptor for theproinflammatory cytokinemacrophage migration inhibitory factor[137]. CD74 is expressed on APCs but also on a diversity of tumors, including B-cell lymphomas, gastric cancer,renal cancerand non-small cell lung cancer. Moreover, CD...