嵌合抗原受体T细胞(chimeric antigen receptor T cell,CAR-T)疗法目前已应用于血液肿瘤的治疗,前期研究发现CD74在白血病患者白血病干细胞中高表达,为了探索其对白血病细胞的杀伤作用,通过CD74 CAR表达载体的构建、慢病毒载体的包装及T细胞的感染,制备CD74 C...
thymic epithelial cells (TECs)Thymic epithelial cells (TECs) are indispensable for T cell development, T cell receptor (TCR) repertoire selection, and specific lineage differentiation. Medullary thymic epithelial cells (mTECs), which account for the majority of TECs in adults, are critical for ...
CD74别名:LN2, HLA-DR-associated invariant chain概述:II型膜蛋白信号定位:胞质、胞膜在病理学中的应用:不典型纤维黄色瘤(-)与恶性纤维组织细胞瘤(+)的鉴别。 B cell marker (not commonly used) 商品化试剂(排名不分先后,本网站对抗体质量不负责!)公司 克隆号 即用型(ml) 原液(ml) 基因科技 LN2 /...
CD74functions as an MHC class II chaperone and is normally expressed by a variety of cell types including B cells, activated T cells, macrophages, activated endothelial cells, and epithelial cells. Although expressed by the H/RSCs of CHL, CD74 is not specific for this lymphoma; expression ha...
产品名称:Ⅱ类主要组织相容性复合体不变链(CD74)真核蛋白多种属 相同的名称,不同的物种,其它种属价格请询价来源 原核表达宿主293F cell内毒素水平 <1.0EU per 1ug (determined by the LAL method)亚细胞定位细胞核, 分泌, 细胞质片段与标签 His129~Arg247 with N-terminal His Tag缓冲液成份 磷酸盐缓冲液(...
is the invariant chain that chaperones MHC class II dimers from the endoplasmic reticulum to the cell surface. CD74 is expressed by cells of both T lymphocyte and B lymphocyte lineages. It is upregulated in several cancers and is also expressed by nonimmune cells during inflammation. Recombinant...
Dendritic cells (DCs) sample peripheral tissues of the body in search of antigens to present to T cells. This requires two processes, antigen processing and cell motility, originally thought to occur independently. We found that the major histocompatibility complex II-associated invariant chain (Ii...
intracellularly processed peptides, present them to T-helper cells, and have a critical role in the initiation of the immune response. 仅用于科研。不用于诊断过程。未经明确授权不得转售。 相关产品 免疫组织化学 Secondary Antibodies 同型对照 IHC封片剂...
应用范围WB,IHC 基因名称CD74 克隆号OTI1G10 抗体来源Mouse 抗体类型IgG1 免疫原Full length human recombinant protein of human CD74(NP_001020330) produced in HEK293T cell. 实际分子量33.3KD 成分PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. ...
Immune cell infiltration analysis Correlations between the copy number variation (CNV) of CD74 and the abundances of six types of tumor-infiltrating immune cells (TIICs) (B cells, CD4 + T cells, CD8 + T cells, neutrophils, macrophages, and dendritic cells) were explored using the ...