CD74: a new candidate target for the immunotherapy of B-cell neoplasms. Clin Cancer Res. 2007;13(18 Pt 2):5556s- 5563s.Stein R, Mattes MJ, Cardillo TM, et al. CD74: a new can- didate target for the immunotherapy of B-cell neoplasms. Clin Cancer Res.2007;131(18 pt 2):5556s...
CD74别名:LN2, HLA-DR-associated invariant chain概述:II型膜蛋白信号定位:胞质、胞膜在病理学中的应用:不典型纤维黄色瘤(-)与恶性纤维组织细胞瘤(+)的鉴别。 B cell marker (not commonly used) 商品化试剂(排名不分先后,本网站对抗体质量不负责!)公司 克隆号 即用型(ml) 原液(ml) 基因科技 LN2 /...
CD74 (B-Cell Marker) Mouse Monoclonal Antibody供应商 MyBioSource产品货号 MBS438989产品报价 ￥询价/0.02mg(WithBSA&Azideat0.2mg/mL) ￥询价/0.1mg(WithBSA&Azideat0.2mg/mL) ￥询价/其它规格产品说明书 点击查看购买方式 MyBioSource中国区金牌代理,部分产品现货库存。银行转账、电汇、支票、现金,在线支付宝...
Lasting B-cell persistence in the periphery is dependent on survival signals that are transduced by cell surface receptors. We recently demonstrated that cell surface CD74 controls mature B-cell survival. Stimulation of cell surface CD74 leads to NF-kappaB activation, which enables entry of the ...
Lasting B-cell persistence in the periphery is dependent on survival signals that are transduced by cell surface receptors. We recently demonstrated that cell surface CD74 controls mature B-cell survival. Stimulation of cell surface CD74 leads to NF-κB activation, which enables entry of the ...
maturation of B-cells[136]. CD74 is also a high-affinity receptor for the proinflammatory cytokine macrophage migration inhibitory factor[137]. CD74 is expressed on APCs but also on a diversity of tumors, including B-cell lymphomas, gastric cancer, renal cancer and non-small cell lung cancer...
MIF and CD74 have been shown to regulate peripheral B cell survival and were associated with tumor progression and metastasis. CD74 expression has been suggested to serve as a prognostic factor in many cancers, with higher relative expression of CD74 behaving as a marker of tumor progression. ...
CD74代表被称为mhcii类相关不变链的II型整合膜蛋白。它在b细胞上适度表达,在单核细胞和巨噬细胞上微弱表达。CD74也存在于活化的T细胞,朗格汉斯细胞,树突状细胞和一些上皮细胞的子集上。CD74可通过II类分子在细胞表面的细胞内转运和表达而在抗原加工和呈递中发挥作用。应用...
The integral role of CD74 in antigen presentation, MIF signal transduction, and B cell survival and homeostasis. Mini-Rev. Med. Chem. 14, 1132-1138... Richard,Bucala,Idit,... - 《Mini Reviews in Medicinal Chemistry》 被引量: 11发表: 2014年 'Role reversal' for the receptor PAR1 in ...
We found that CD74 is expressed broadly in normal B‐cell compartments including primary and secondary lymphoid follicles and in the thymic medulla. The vast majority of lymphomas expressed CD74, including Hodgkin lymphomas (98%), B‐cell lymphomas (96%), extranodal NK/T‐cell lymphomas (88%)...