嵌合抗原受体修饰的T细胞;CD74;急性髓系白血病;白血病干细胞 白血病干细胞(leukemia stem cell,LSC)是白血病复发难治的重要根源之一,其作为少数具有自我更新潜能并抵抗化疗的一群白血病细胞,长期的自我更新能力可驱动克隆生长。LSC表现出特定的表型,特别是在...
Cancer stem cellsThe 纬 subunit of the major histocompatibility complex (MHC) class II complex, CD74, is overexpressed in a significant proportion of metastatic breast tumors, but the mechanistic foundation and biologic significance ...
肝干细胞( hepatic stem cell,HSC) 又称肝祖细胞,是肝细胞大片坏死时最早的补充与修复细胞源, 也被认为是未来肝细胞移植治疗终末期肝病最有前途的细胞源之一[2-4]。 但由 于HSC 的特异性标志物尚不明确, 且正常情况下肝组织中 HSC 数量极少, 极大地限制了 HSC 的分离与应用[4]。 本研究通过改进的胶原酶...
原文出处 Borrelli MR, Patel RA, Adem S, et al. The antifibrotic adipose-derivedstromal cell: Grafted fat enriched withCD74+adipose-derived stromal cellsreduces chronic radiation-induced skin fibrosis.Stem Cells TranslMed. ...
关键词: Esophageal cancer Radiotherapy Response Chemoradiotherapy Cancer stem cells DOI: 10.1593/neo.13464 被引量: 3 年份: 2013 收藏 引用 批量引用 报错 分享 全部来源 求助全文 EBSCO leaddiscovery.co.uk 相似文献 参考文献 引证文献Macrophage migration inhibitory factor (MIF) promotes cell survival by ...
Stem Cell Res Ther DPSCs regulate epithelial-T cell interactions in oral submucous fibrosis Authors - S Y Wang View Article WB Int Immunol Helicobacter urease suppresses cytotoxic CD8 + T cell responses through activating Myh9-dependent induction of PD-L1. Authors - Jian Wu View Article IF Neural...
the recent advent of advanced imaging studies has led to the identification of unique niches that provide a highly specialized microenvironment for distinct hematopoietic developmental processes. These include anatomically defined niches forhematopoietic stem cells[102,103], and forB cell development[104]....
TAp63α mediates chemotherapeutic agent-induced apoptosis in human bone marrow mesenchymal stem cells. Human bone marrow-derived mesenchymal stem cells (MSCs) are currently widely used in cell therapy and tissue engineering. In vitro experiments have demonst... CC Lu - 《Stem Cells & Development》...
Mounting evidence suggests that gliomas are comprised of differentiated tumor cells and brain tumor stem cells (BTSCs). BTSCs account for a fraction of tot... A Wu,S Wiesner,J Xiao,... - Journal of Neuro-Oncology 被引量: 229发表: 2007年 Non-mitogenic T-cell activation signals are suffic...
The CXCL12/CXCR4 axis is involved in homeostatic and inflammatory cell migration processes, including inflammatory and atherogenic T cell recruitment, stem cell homing, and cancer cell metastasis [12], [13]. G protein-coupled receptors regulate MAPK signalling pathways that result in the expression ...