Pharmacological Inhibition of Ferroptosis as a Therapeutic Target for Neurodegenerative Diseases and Strokes 药理学抑制铁死亡:神经退行性疾病与中风的治疗靶点 Targeted xCT-mediated Ferroptosis and Protumoral Polarization of Macrophages Is Effective...
Immunotherapy has demonstrated significant potential for the treatment of patients with chemotherapy-resistant hematologic malignancies and solid tumors. One type of immunotherapy involves the adoptive transfer of T cells that have been genetically modified with a chimeric antigen receptor (CAR) to target ...
IMMUNOTHERAPY FOR CANCERDisclosed is a composition comprising an immunogenic composition for use in treatment of squamous cell carcinoma in combination with myeloid-derived suppressor cell-inhibiting agents as well as a corresponding method of treatment.Irena ADKINS...
Targeting Tyro3, Axl and MerTK (TAM receptors): Implications for macrophages in the tumor microenvironment Tumor-associated macrophages are an abundant cell type in the tumor microenvironment. These macrophages serve as a promising target for treatment of cancer... KV Myers,SR Amend,KJ Pienta - 《...
2 Additionally, the CD6 ligand, activated leukocyte cell adhesion molecule (ALCAM), is expressed on antigen-presenting cells and tissues. Both CD6 and ALCAM are overexpressed during gastrointestinal inflammation, and prior clinical studies have pointed to CD6 relevant target for the pathogenesis of ...
审批编码:C-APROM/CN/ADCE/1223 2024年3月 *仅供医疗卫生专业人士使用 维布妥昔单抗简明处方 参考文献 1.Hu H, Wang K, Jia R, et al. Current Status in Rechallenge of Immunotherapy. Int J Biol Sci. 2023;19(8):2428-2442. ...
Passive immunotherapy of cancer in animals and man. Therefore, passive therapy is regarded as an attractive area of investigation in tumor immunotherapy. The chapter summarizes the existing information concerning the use of subcellular products, such as immune RNA or transfer factor, in the ... SA...
γδT cells have been reported to exert immunosuppressive functions in multiple solid malignant diseases, but their immunosuppressive functional subpopulation in breast cancer (BC) is still undetermined. Here, we collected 40 paired BC and normal tissue samples from Chinese patients for analysis. First...
With a preferential expression on tumor cells, B7-H3 is an attractive target for cancer immunotherapy. Based on the clinical success of inhibitory immune checkpoint blockade (CTLA-4, PD-1, and PD-L1), mAbs against B7-H3 appear to be a promising therapeutic strategy worthy of development. An...
这场学术饕餮盛宴,不容错过! 参考文献: [1] CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy. Nature. 2019. DOI: 10.1038/s41586-019-1456-0 https://www.nature.com/articles/s41586-019-1456-0 推荐内容