Records of circulating CD16+CD56+natural killer (NK) cells were analyzed before and after the initial chemotherapy of FOLFOX plan. Patients were followed up until June 30, 2019. One hundred and twenty-four cases after the FOLFOX chemotherapy were enrolled into this study. There were no ...
CD3-CD16-CD56bright immunoregulatory NK cells are increased in the tumor microenvironment and inversely correlate with advanced stages in patients with pap... CD3- CD16-CD56bright immunoregulatory NK Cells are increased in the tumor microenvironment and inversely correlate with advanced stages in pa- ...
In contrast to peripheral blood lymphocytes (PBLs), the majority of NK cells from the synovial fluid were CD56brightCD16(−) cells. As expected the expression of the cytolytic mediators perforin and granzyme B in CD56brightCD16(−) cells was low and correlated with a poor cytotoxic potenti...
We also found that viable NKreg cells may be isolated by sorting on CD56+ and CD16- NK cells, and this population can suppress allogeneic CD4+ T cells, but not Treg cells or CD8+ T cells through a non-cytolytic, cell-cell contact dependent mechanism. Suppression was not reliant upon ...
Molecular Cancer (2024) Potential anti-tumor effects of regulatory T cells in the tumor microenvironment: a review Yu Li Cangang Zhang Peng Luo Journal of Translational Medicine (2024) Regulatory T cell-mediated immunosuppression orchestrated by cancer: towards an immuno-genomic paradigm for precisi...
Since the expression of CD56 serves better than CD161 positivity in defining an NK receptor-positive T cell subpopulation (Norris et al., 1999), we have defined “NKT-like cells” as CD3+CD56+ cells in this study, rather than as CD3+CD161+ cells. T cells expressing CD56 marker are not...
Objective: To detect the proportion of natural killer T(NKT) cells (CD3(superscript +)CD16(superscript +)CD56(superscript +)) in peripheral blood among healthy adults by flow cytometry. Methods: The whole peripheral blood of 141 healthy adults and 30 patients with lung cancer were collected and...
Human NK cells comprise approximately 10% of peripheral blood lymphocytes and are characterized phenotypically by the presence of CD56 and the lack of CD3. The majority (approximately 90%) of human NK cells are CD56dimand express high levels of FcγRIII (CD16), whereas a minority (approximatel...
Expression of CD3ϵ, CD3ζ, and RAG-1/RAG-2 in Decidual CD56+NK Cells In early pregnancy the uterine mucosa, the decidua, is infiltrated by numerous CD56bright, CD16−natural killer (NK) cells. In this paper we have shown t... Ashley,King,and,... - 《Cellular Immunology》 被引...
specifically CD94/NKG2A and certain killer-cell immunoglobulin-like receptors (KIRs), that prevent activation of NK cells upon binding to MHC class I molecules on the target cell. Upon downregulation of MHC class I, e.g., in virus-infected or cancerous cells, NK cells will be triggered by...