Assuming that 60 to 70% of the cells are nonproliferating CD68-positive macrophages, this shows that locally a high number of synovial fibroblasts could proliferate and contribute to synovial hyperplasia.7, 8, 22 However, the expression of anti-apoptotic molecules such as Flice inhibitory protein ...
5f for classification) demonstrated a higher percentage of neutrophil elastase (NE)- and calprotectin (S100A8/A9)-positive cells, but not PDPN-positive stromal cells or CD68+ MNPs (Fig. 3g). High M4/M5 expression in whole tissue thus reflects ulceration characterized by a predominance of ...
Consistent with these results, vehicle-treated SuHx rats also exhibited an increase in the Fulton index, in RV picrosirius staining, and in the percentages of muscularized distal pulmonary arteries together with higher numbers of CD68 and PCNA positive cells (Figure 2A–C and Figure 3A,B). ...