These CD138(int) B cells were IgM(low)IgD(high) mature B cells, located within follicular B cell zone, and expressed a lower level of CD21 than CD138- follicular B cells. During in vitro culture of splenic cells, the proportion of CD138(Int) B cells increased, which was noticeably ...
Resources and Publications Related Products Overview Isolate highly purified mouse CD138+ cells from mouse splenocytes, lymph nodes, or bone marrow samples by immunomagnetic positive selection, with the EasySep™ Mouse CD138 Positive Selection Kit. Widely used in published research f...
G rouP w as evidentl y high er than thatof Plasm a cells of C ontro lGr ouP.Th e d ifl七rence b etw een tw o grouPs 15 of statistieal signifieanee , P < 0 .05 . Th e rate in stage 11 and 111 w as signifieantly higher than that in stage l , ail ...
CD138 is a transmembrane protein containing chondroitin sulfate and heparin sulfate moieties responsible for binding to the extracellular matrix components. CD138 is not expressed by mature B cells but is present on pre-B cells and the finally differentiated plasma cells.Applications Reported: DL-...
The DL-101 monoclonal antibody specifically reacts with human CD138, a 85-92 kDA type I heparan sulfate proteoglycan. CD138 is known as Syndecan-1 and is expressed on pre-B cells, immature B cells, plasma cells, and malignant plasma cells, to the exclusi
Little is known about their effects on B cells and humoral immune responses. We show that CS but not dextran or other glycosaminoglycans induces a pronounced proliferation of B cells in vitro compared with TLR4 or TLR9 ligands. With the use of inhibitors and KO mice, we demonstrate that this...
Clone No B-B4 Leadtime Inquire Verified Samples Verified Samples in FCM: U266 Dilution FCM 2 μg/mL(1×10<sup>5</sup>-5×10<sup>5</sup> cells) Background Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstiti...
It participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a heparan sulfate proteoglycan expressed on the surface of, and actively shed by, myeloma cells. Altered syndecan-1 expression has been detected in several ...
The cluster of differentiation antigen (CD Antigens) 138 or syndecan-1 (Syndecans) refers to a cell marker present on the surface of normal and malignant plasma cells as well as the basolateral surface of endothelial cells. It is not however, detected on naïve nor memory B cells, T cell...
CD138 was regarded as a useful marker for labeling normal and neoplastic plasma cells and plasmacytoid lymphomas. CD138 has a calculated molecular weight of 32.5 kDa, the apparent molecular weight is higher due to extensive glycosylation. 实验方案 Product Specific Protocols WB protocol for CD138/...