CD138-negative clono- genic cells are plasma cells but not B cells in some multiple myeloma patients. Leukemia. 2012; 26 (9):2135-41. doi: 10.1038/leu.2012.80 PMID: 22430638Hosen N, Matsuoka Y, Kishida S, Nakata J, Mizutani Y, Hasegawa K, et al. CD138-negative clonogenic cells are...
However, its sensitivity is hampered due to paucity of plasma cells in whole bone marrow and often shows false-negative results when frequency of abnormal cells is below the cut-off values. Studies have shown that the abnormality detection rate in enriched plasma cells (EPC) is greater than ...
The canonical plasma cell marker CD138 (syndecan-1) is highly expressed on the myeloma cell surface, but its functional role in vivo is unclear, as well as the ontogeny of CD138-high and CD138-negative (neg) myeloma cells. In this study we used an in vivo murine Vk*MYC myeloma model...
目的探索既往胚胎移植未孕患者宫腔镜子宫内膜活检和CD38、CD138联合筛查慢性子宫内膜炎(chronic endometritis,CE),治疗后再次胚胎移植的妊娠结局。 方法采用回顾性队列研究,收集2015年1月1日至2018年12月31日期间,在北京大学第三医院妇产科...
CD138 is not expressed by mature B cells but is present on pre-B cells and the finally differentiated plasma cells.Applications Reported: This MI15 antibody has been reported for use in flow cytometric analysis.Applications Tested: This MI15 antibody has been pre-diluted and tested by flow...
www.nature.com/scientificreports OPEN Received: 29 January 2019 Accepted: 14 August 2019 Published: xx xx xxxx CD138 plasma cells may predict brain metastasis recurrence following resection and stereotactic radiosurgery Michael H. Soike1, Jennifer Logue2, Shadi Qasem3, Ryan T. Hughes...
plasma cellsbyflow~~ometry.Result:ThePRDM1expressioninSLEpatientsbloodwassignificantlyhigherthanthathealthy"group(P<0.05),andtheamountof CD138 plasmacellsarealsomorethanhealthygroup.Conclusion:PRDMIandtheamountofCD138 plasmacellsinSLEstudygroupissignificantlyhigher thancontrolgroup,indicatingthatthehighPRDM1expre...
plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a ...
Tumor growth need not be driven by rare cancer stem cells. Science 2007; 317: 337. Article CAS Google Scholar Reid S, Yang S, Brown R, Kabani K, Aklilu E, Ho PJ et al. Characterisation and relevance of CD138-negative plasma cells in plasma cell myeloma. Int J Lab Hematol 2010; ...
Likewise, the fraction of CD19+ B cells (9.4%, normal 12.7 ± 5.4%) and CD138+ plasma cells (0.16%, normal 0.17 ± 0.14%) were normal in the PB. In contrast, flow cytometry of the CSF (Figure 1G, lower panels, CSF) revealed predominantly CD3+ CD56- T cells (95%...