CD11b(+) Gr1(+) bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice. Hepatology 2012; 56: 1902-1912 [PMID: 22544759 DOI: 10.1002/hep.25817]Suh, Y.G., et al. CD11b(+) Gr1(+) bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice. ...
答:Gr-1单抗通常认为是粒细胞标记,但实际上,它既可结合Ly-6G也可结合Ly-6C。大多数 Gr1+ CD11b- 细胞是 Ly6C+ LyG-,Ly6C可表达在浆细胞、部分粒细胞和T 细胞(包括记忆 T 细胞)表达。所以Gr1+ CD11b-细胞可能CD8是阳性的,如果补做CD8是阳性的...
We were led to conclude that WBI can significantly decrease the accumulation of CD11b+Gr-1+cells in the spleen, reduce the infiltration of Gr1+CD11b+ cells in the tumor and finally delay the tumor re-growth after irradiation. Elimination of CD11b+ myelomonocytic cells-derived neovasculature by...
Gr1(+)CD11b(+) cells expressed high levels of arginase-1, and IL-17, additional markers of myeloid derived suppressor cells. We then sorted the Gr1(hi) and Gr1(int) populations from M. tuberculosis infected NOS-/- mice and placed the sorted both Gr1(int) populations at different ratios ...
CD11b+ Gr1dim cells were transferred to ZyA-treated SKG mice.MDSCs, Th17 cells, and group 1 and 3 innate lymphoid cells (ILC1s and ILC3s) were increased in the lungs; the proportion of these cells varied with ILD severity. In this process, we found that a unique cell population, CD...
Methods: The expression of F4/80, CD11b, Gr1in monocytes from tumor, other tissue and peripheral blood were detected by flow cytometry. Transwell, real-time PCR, western-blot and flow cytometry analysis were used to observe the functional changes of F4/80+CD11b+Gr-1+ cells in tumor ...
肿瘤微环境中F480CD11bGr1单核细胞活化机制的研究 华中科技大学 博士学位论文 肿瘤微环境中F4/80+CD11b+Gr-1+单核细胞活化机制的研究 姓名:*** 申请学位级别:博士 专业:生物化学与分子生物学 指导教师:**化 2010-05华中科技大学同济医学院博士研究生学位论文 +++ 肿瘤微环境中F4/80CD11bGr-1 单核细胞活化...
采用小鼠4T1乳腺癌模型观察MSC通过CD11b+Gr1+细胞对肿瘤生长的影响.结果 MSC能够促进骨髓中CD11b+Gr1+细胞的存活和生成,同时可诱导正常小鼠骨髓中CD11b+Gr1+细胞对T细胞的抑制作用.动物实验结果显示,MSC处理后的骨髓CD11b+Gr1+细胞可以促进肿瘤的生长,加速小鼠的死亡.结论 MSC可以通过促进骨髓来源的CD11b+Gr1+细...
Gr-1(+) cells could be found on the edges of necrotic lung lesions in NOS2-/-, RAG-/-, and C3HeB/FeJ, but were absent in wild-type mice. Both populations of Gr1(+)CD11b(+) cells expressed high levels of arginase-1, and IL-17, additional markers of myeloid derived suppressor ...
CD11b+ Gr1+ bone marrow cells ... GS Yang,JK Kim,SB Jin,... - 《Hepatology Official Journal of the American Association for the Study of Liver Diseases》 被引量: 0发表: 2012年 CD11b+ Gr1+ bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice†‡ et al....