cellshadno beneficialeffectonendothelialfunction.InApoE −/− -CD11b-DTR-micewithahypercholesterolemia-induced chronicendothelialinjurytransfusionofWT-derivedCD11b + -monocytesstimulatedbyinterferon-γ(IFNγ) decreasedendothelialfunction,whereasinterleukin-4-stimulated(IL4)monocyteshadnodetectableeffect on...
CD11[b.sup.+]Ly6[C.sup.++]Ly6[G.sup.-] cells with suppressive activity towards T cells accumulate in lungs of influenza a virus-infected miceFluorochrome-coupled antibodies recognizing mouse CD3 (clone 145-2C11), CD4 (RM4-5), CD11b ...
Interferon-producing killer dendritic cells (IKDCs) are a recently described subset of CD11cloB220+cells that share phenotypic and functional properties of DCs and natural killer (NK) cells (Chan, C.W., E. Crafton, H.N. Fan, J. Flook, K. Yoshimura, M. Skarica, D. Brockstedt, T.W....
Leukocyte integrins and intercellular adhesion molecules play pivotal roles in leukocyte adhesion to target cells and extracellular matrices. Recently, nov... CG Gahmberg - 《Curr.opin.cell Biol》 被引量: 498发表: 1997年 Leukocyte adhesion: CD11/CD18 integrins and intercellular adhesion molecules Le...
Variable expression of activation-linked surface antigens on human mast cells in health and disease Summary: Mast cells (MC) are multipotent effector cells of the immune system. They contain an array of biologically active mediator substances in their gra... P.,Valent,G.-H.,... - 《Immunolo...
Juxtacrine interactions of endothelial cells with leukocytes: Tethering and signaling molecules One consequence of juxtacrine activation of PMNs by PAF is functional upregulation of CD11/CD18 integrins on the PMN. These integrins bind to counter... KD Patel,E Lorant,DA Jones,... - 《Behring Inst...
Of four anti-rabbit CD18 Mabs tested, only one, L13/64, has been shown to be capable of inhibiting the adhesion of fMLP-stimulated neutrophils to gelatin coated plastic and the homotypic aggregation of PMA-stimulated T cells, both of which assays have been shown to be CD18-dependant. RC...
Adhesion molecules of the CD11 cluster play an important role in adherence of neutrophils to endothelial cells in inflammation. We conducted a haplotype-based analysis of the CD11 cluster in a sample of 315 patients with H. pylori infection and investigated associations with gastric erosions and ...
In contrast, a panel of different MoAbs to CD11a had no significant inhibitory effect on ADCC, a finding consistent with the low-to-absent expression of the CD11a ligand, intercellular adhesion molecule-1, on the target cells. Granulocyte-macrophage colony-stimulat-ing factor (GM-CSF) ...
We have examined the contributions of endothelial-leukocyte adhesion molecule-1 (ELAM-1) and the complex of leukocyte surface adhesion molecules designated CD11/CD18 to the adhesion of human polymorphonuclear leukocytes (PMN) to cultured human endothelial cells (HEC), activated by rIL-1 beta for ...