CD11c(+)CD8 alpha and CD11c(+)CD11b(+) dendritic cells are two major subsets of murine splenic CD11c(+) DCs which play a crucial role in T cell priming and shaping Th1/Th2 responses, but their role in the context of experimental visceral leishmaniasis (VL) is poorly understood. Herein,...
in vivo targeting of dendritic cells, Immunohistochemistry (frozen) Castro FV, Tutt AL, White AL, Teeling JL, James S, French RR, Glennie MJ. (2008). "CD11c provides an effective immunotarget for the generation of both CD4 and CD8 T cell responses" Eur J Immunol 38(8):2263-73....
in vivo targeting of dendritic cells, Immunohistochemistry (frozen) Castro FV, Tutt AL, White AL, Teeling JL, James S, French RR, Glennie MJ. (2008). "CD11c provides an effective immunotarget for the generation of both CD4 and CD8 T cell responses" Eur J Immunol 38(8):2263-73....
in vivo targeting of dendritic cells, Immunohistochemistry (frozen) Castro FV, Tutt AL, White AL, Teeling JL, James S, French RR, Glennie MJ. (2008). "CD11c provides an effective immunotarget for the generation of both CD4 and CD8 T cell responses" Eur J Immunol 38(8):2263-73....
(Wakim, Waithman, van Rooijen, Heath, & Carbone, 2008). However, the relative roles of steady-state CD11b+DCs and infiltrating inflammatory CD11b+DCs in activating memory CD8+T cell response have not been delineated (Wakim et al., 2008). CD11b+DCs in the skin and CD103+CD11b+...
cancers Article CD11c-CD8 Spatial Cross Presentation: A Novel Approach to Link Immune Surveillance and Patient Survival in Soft Tissue Sarcoma Yanhong Su 1, Panagiotis Tsagkozis 2, Andri Papakonstantinou 1,3, Nicholas P. Tobin 1 , Okan Gultekin 4 Anna Malmerfelt 1, Katrine Ingelshed 4, Shi ...
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目的研究日本血吸虫可溶性虫卵抗原(SEA)免疫小鼠CD11c+CD8α-树突状细胞(DC)亚群对卵清白蛋白(OVA)诱发的过敏性哮喘的抑制作用.方法 BALB/c小鼠经腹腔及足垫注射SEA 50μg/只,每周1次,共4次.用抗体包被的免疫磁珠分离小鼠脾CD11c+CD8α+DC与CD11c+CD8α-DC亚群.另取18只BALB/c小鼠,随机分为4组,A组为健康对...
Taken collectively, current findings indicate thatCD11c+CD8+T cells, which are the main agents of anti-4-1BB mAb therapy, function sometimes as immune regulators by suppressing CD4+T cellnumbers/function, and sometimes as immune effectors. Interestingly, in both cases their activities are beneficial...
日本血吸虫尾蚴感染小鼠CD8α - CD11c +型树突状细胞对哮喘的抑制作用