A cDNA encoding a cathepsin L-like cysteine proteinase (DcCathL) was prepared from gut tissue of larvae of wheat bulb fly ( Delia coarctata: Diptera). The predicted protein is a homologue of the product of Drosophila melanogaster gene Cp-1 (CG6692), and is similar to a sub-family of ...
Two cathepsin L-related cysteine proteinase molecular clones were isolated from cDNA libraries of mRNA from the eyestalk nervous system and the stomach of ... CL Boulay,AV Wormhoudt,D Sellos - 《Comp Biochem Physiol B Biochem Mol Biol》 被引量: 74发表: 1995年 The Novel Bovine Serpin Endopin...
(redirected fromCathepsin L) Medical Encyclopedia ca·thep·sin (kə-thĕp′sĭn) n. Any of various enzymes found in animal tissue that catalyze the hydrolysis of proteins into smaller proteins. [GermanKathepsin, from Greekkathepsein,to digest:kat-, kata-,cata-+hepsein,to boil.] ...
Both genes are about 1.2 kb in size and show high sequence homology predominantly to invertebrate cathepsin L-like cysteine proteinases. 展开 关键词: cathepsin L-like cysteine proteinase Haemaphysalis longicornis tick vaccine DOI: 10.1292/jvms.61.497 被引量: 62 ...
Thecathepsinsare papain-like cysteineproteasesand include 11 members (cathepsin B, C, F, H, K, L, O, V, X, S, and W) that are ubiquity expressed in the human body and are involved in a broad spectrum ofphysiological processes, such aswound healing, enzymatic andprohormoneactivation,prote...
Cathepsin L in metastatic bone disease: therapeutic implications Cathepsin L is a lysosomal cysteine proteinase primarily devoted to the metabolic turnover of intracellular proteins. However, accumulating evidence sugges... G Leto,MV Sepporta,M Crescimanno,... - 《Biological Chemistry》 被引量: 57...
This points to mammalian cathepsins as likely physiological targets of a novel cysteine-proteinase inhibitor expressed on bacterial cell surface. Both papain and mammalian cathepsins L and B were inhibited by periplasmic extracts of aerobically and anaerobically grown bacteria, the inhibitory activity ...
Finally, we have recently reported the finding of cathepsin L2, a cysteine proteinase structurally related to cathepsin L, but showing a unique tissue distribution (21). In this study, we report the identification, chromosomal location, and structural and enzymatic characterization of a novel member...
Amylase, maltase and the cysteine proteinase occur in the gut contents and decrease throughout the midgut; trypsin is constant in the entire midgut, whereas a membrane-bound aminopeptidase predominates in the posterior midgut. The cysteine proteinase was purified to homogeneity through ion-exchange ...