The dominant intestinal transcripts were represented by cathepsin B-like cysteine protease genes ( cbl) (17% of protein coding expressed sequence tags (ESTs) analyzed). An estimated 11 previously undescribed cbl genes were identified, doubling the recognized members of this gene family. Multiple C-...
Cathepsin B-like cysteine proteaseCryopreservation-induced cell deathProgrammed cell deathHydrogen peroxideCryo-injuryCell death is an inevitably cryo-injury in cell and tissue cryopreservation. The research on programmed cell death (PCD) in plant cryopreservation is still in its infancy. In this study,...
While the over-expression of the metallopeptidase neprilysin or of the insulin-degrading enzyme protects model mice from AD-like disease25, CTSB, a papain-like cysteine protease that is synthesized as a preproenzyme47, promotes the development and progression of AD. Hence, the knockout of CTSB...
L. Isolation and characterization of four developmentally regulated cathepsin B-like cysteine protease genes from the nematode Caenorhabditis elegans. DNA Cell Biol. 15, 75–82 (1996) Article CAS PubMed Google Scholar Lorimore, S. A., Rastogi, S., Mukherjee, D., Coates, P. J. & Wright,...
While the activities of certain proteases promote proteostasis and prevent neurodegeneration-associated phenotypes, the protease cathepsin B (CTSB) enhances proteotoxicity in Alzheimer’s disease (AD) model mice, and its levels are elevated in brains of
Cowpea bruchids (Callosobruchus maculatus) strongly induce C.聽maculatus cathepsin B-like cysteine protease 1 (CmCatB1) transcripts when fed diet containing a soybean cysteine protease inhibitor soyacystatin N (scN). CmCatB1 shares significant sequence similarity with cathepsin B-like cysteine ...
Expression levels of the papain-like cysteine protease cathepsin B (Ctsb) have been positively correlated with mammary tumour progression and metastasis; however, its roles in the hallmark processes of malignant growth remain poorly defined. Using Ctsb-deficient mice we investigated tumour cell differen...
Cho WL, Tsao SM, Hays AR, Walter R, Chen JS, Snigirevskaya ES, Raikhel AS: Mosquito cathepsin B-like protease involved in embryonic degradation of vitellin is produced as a latent extraovarian precursor. J Biol Chem 1999, 274(19):13311–13321. 10.1074/jbc.274.19.13311 Article CAS PubMe...
[Regulation of neoplasm-specific cathepsin B by cysteine-protease inhibitors present in cancerous exudates] 来自 NCBI 喜欢 0 阅读量: 12 作者:D Keppler,M Pagano,V Daletfumeron,R Engler 摘要: The Cathepsin B-like proteinase, a secretory form of lysosomal cathepsin B, is present in some cancer...