The title of my presentation, as you may have seen, is "High Glucose Metabolism Fuels Cathepsin L Maturation to Promote SARS-CoV-2 Infection in Patients with Diabetes." Cathepsin L, abbreviated as CTSL, is a lysosomal cysteine protease that plays a crucial role in intracellular protein catabolis...
Radation. Human chymotrypsin C (CTRC) is usually a pancreatic serine protease that regulates activation... Post Categories Uncategorized Post dateJuly 31, 2024Post last updated dateUpdated July 31, 2024 994299).The crystallographic metric parameters of complicated Zn(HPD1)2 are comparable to Po...
RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook cathepsin Medical Acronyms Encyclopedia Wikipedia Related to cathepsin:Cathepsin C ca·thep·sin (kə-thĕp′sĭn) n. Any of various enzymes found in animal tissue that catalyze the hydrolysis of proteins into ...
P. (2007) Cathepsin L activity controls adipo- genesis and glucose tolerance. Nat. Cell Biol. 9, 970 -977Yang M, Zhang Y, Pan J, Sun J, Liu J, Libby P, Sukhova GK, Doria A, Katunuma N, Peroni OD, Guerre-Millo M, Kahn BB, Clement K, Shi GP. Cathepsin L activity controls ...
Cathepsin X is a cysteine-containing cathepsin protease with carboxypeptidase activity. From:Biochemical Pharmacology,2021 About this page Add to MendeleySet alert Chapters and Articles You might find these chapters and articles relevant to this topic. ...
A method of inhibiting activity of a cathepsin L-like protease in cells or tissue and the use of the method in the treatment of disease such as cancer and inflammatory diseases is described. The method comprises administration of a cathepsin propeptide or a nucleic acid encoding a cathepsin ...
We conclude that the activity of cathepsin L is high in the nucleus of colorectal carcinoma cells because of lacking stefin B inhibitory activity. Furthermore, we hypothesize that nuclear cathepsin L accelerates cell cycle progression of HCT116 cells thereby supporting the notion that cysteine ...
Article: Cathepsin B-like activity predominates over cathepsin L-like activity in adult Schistosoma mansoni and S. japonicum
The cysteine protease activity was identified as cathepsin L by affinity labeling with an activity-based probe for cysteine proteases followed by mass spectrometry for peptide sequencing. Production of [Met]enkephalin by cathepsin L occurred by proteolytic processing at dibasic and monobasic prohormone...
Cathepsin L (CTSL), a member of the lysosomal cysteine protease, contains an L domain of α-helix and an R domain of β-sheet in the spatial structure.15Its main function is proteolysis of protein antigens produced by pathogen endocytosis.16Previous studies have indicated that membrane fusion ...