F. The cysteine protease cathepsin B in cancer. Perspect. Drug Discov. Des. 6:12–32; 1996.Elliott E, Sloane BF. The cysteine protease cathepsin B in cancer. Perspect Drug Disc Design 1996;6:12 - 32.Elliott E and Sloane BF, 1996, The cysteine protease cathepsin B in cancer. Perspect...
The cysteine protease CPR-4, a cathepsin B homologue, is identified as a radiation-induced bystander effect (RIBE) factor in nematodes in response to ultraviolet or ionizing radiation, and causes inhibition of cell death and increased embryonic lethality
Odanacatib(Cysteine Protease抑制剂)是有效,选择性的组织蛋白酶K抑制剂,IC50分别为0.2 nM和1 nM。对脱靶的cathepsin B,L,S具有高度选择性。 在体外,Odanacatib作用于组织蛋白酶K具有高抑制活性和选择性,作用于人和兔组织蛋白酶K时,IC50分别为0.2 nM和1 nM。而且,在全部人细胞酶实验中,Odanacatib也同样有效,IC50...
Odanacatib(Cysteine Protease抑制剂)是有效,选择性的组织蛋白酶K抑制剂,IC50分别为0.2 nM和1 nM。对脱靶的cathepsin B,L,S具有高度选择性。在体外,Odanacatib作用于组织蛋白酶K具有高抑制活性和选择性,作用于人和兔组织蛋白酶K时,IC50分别为0.2 nM和1 nM。而且,在全部人细胞酶实验中,Odanacatib也同样有效,IC50为...
Cathepsin B-like cysteine proteaseCryopreservation-induced cell deathProgrammed cell deathHydrogen peroxideCryo-injuryCell death is an inevitably cryo-injury in cell and tissue cryopreservation. The research on programmed cell death (PCD) in plant cryopreservation is still in its infancy. In this study,...
324 Joyce and colleagues demonstrated that TAM protease activity of cathepsin B and cathepsin S enhances pancreatic tumor growth, angiogenesis, and invasion.325 Cathepsin S has been implicated in T cell selection in the thymus.326 Cathepsin Z (also known as cathepsin X) exopeptidase activity has ...
Odanacatib(Cysteine Protease抑制剂)是有效,选择性的组织蛋白酶K抑制剂,IC50分别为0.2 nM和1 nM。对脱靶的cathepsin B,L,S具有高度选择性。在体外,Odanacatib作用于组织蛋白酶K具有高抑制活性和选择性,作用于人和兔组织蛋白酶K时,IC50分别为0.2 nM和1 nM。而且,在全部人细胞酶实验中,Odanacatib也同样有效,IC50为...
E-64_半胱氨酸蛋白酶(cysteine protease)抑制剂_66701-25-5_Apexbio
- 《Journal of Physical Chemistry B》 被引量: 7发表: 2015年 A murrel cysteine protease, cathepsin L: bioinformatics characterization, gene expression and proteolytic activity Cathepsin L, a lysosomal endopeptidase, is a member of the peptidase C1 family (papain-like family) of cysteine proteinases...
产品描述 Odanacatib (MK-0822)是一种有效的,选择性的,cathepsin K(人/兔)中性抑制剂,IC50为0.2nM/1nM,对脱靶的cathepsin B、L、S具有高度选择性。Phase 3。 信号通路 Proteases 靶点 Cathepsin K (human) Cathepsin K (rabbit) - - - IC50 0.2nM 1nM - - - 体外研究 在体外,Odanacatib作用于组织...