In actuality, the cathepsin family also contains members of the serine protease (cathepsin A, G) and aspartic protease (cathepsin D, E) families as well. These enzymes exist in their processed form as disulfide-linked heavy and light chain subunits with molecular weights ranging from 20-35 kDa...
The cysteine protease CPR-4, a cathepsin B homologue, is identified as a radiation-induced bystander effect (RIBE) factor in nematodes in response to ultraviolet or ionizing radiation, and causes inhibition of cell death and increased embryonic lethality
Cathepsin B-like cysteine proteaseCryopreservation-induced cell deathProgrammed cell deathHydrogen peroxideCryo-injuryCell death is an inevitably cryo-injury in cell and tissue cryopreservation. The research on programmed cell death (PCD) in plant cryopreservation is still in its infancy. In this study,...
Cysteine Protease,即半胱氨酸蛋白酶,也称为硫醇蛋白酶,是降解蛋白质的水解酶。一般存在于溶酶体,主要参与细胞吞噬和细胞内多余物质的清除和消化。 有研究表明,Cysteine Protease抑制剂具有很好的生物防御作用,能参与各种生理和病理的过程,如风湿性关节炎、肾衰竭、骨质疏松症、肿瘤的侵袭...
CA-074 methyl ester (Cathepsin B Inhibitor IV) 是Cathepsin B 的选择性抑制剂,具有保护神经、抗炎、抗癌等多种作用。
Odanacatib(Cysteine Protease抑制剂)是有效,选择性的组织蛋白酶K抑制剂,IC50分别为0.2 nM和1 nM。对脱靶的cathepsin B,L,S具有高度选择性。在体外,Odanacatib作用于组织蛋白酶K具有高抑制活性和选择性,作用于人和兔组织蛋白酶K时,IC50分别为0.2 nM和1 nM。而且,在全部人细胞酶实验中,Odanacatib也同样有效,IC50为...
Odanacatib(Cysteine Protease抑制剂)是有效,选择性的组织蛋白酶K抑制剂,IC50分别为0.2 nM和1 nM。对脱靶的cathepsin B,L,S具有高度选择性。 在体外,Odanacatib作用于组织蛋白酶K具有高抑制活性和选择性,作用于人和兔组织蛋白酶K时,IC50分别为0.2 nM和1 nM。而且,在全部人细胞酶实验中,Odanacatib也同样有效,IC50...
The aim of this study was to determine the involvement of cathepsin B and its inhibitors in the proteolytic degradation of human osteoarthritic (OA) tissue. The characteristics of the cathepsin B fou...
Odanacatib(Cysteine Protease抑制剂)是有效,选择性的组织蛋白酶K抑制剂,IC50分别为0.2 nM和1 nM。对脱靶的cathepsin B,L,S具有高度选择性。在体外,Odanacatib作用于组织蛋白酶K具有高抑制活性和选择性,作用于人和兔组织蛋白酶K时,IC50分别为0.2 nM和1 nM。而且,在全部人细胞酶实验中,Odanacatib也同样有效,IC50为...
Protease/Metabolic Enzyme--Cathepsin CAS号(CAS NO.) 88321-09-9 分子式(Formula) C17H30N2O5 分子量(Molecular Weight) 342.43 外观(Appearance) 粉末 纯度(Purity) ≥98% 溶解性(Solubility) 溶于DMSO 结构式(Structure) 运输和保存方法 -25~-15℃保存,有效期3年。