Caspase 3 activation is essential for neuroprotection in precondition- ing. Proc Natl Acad Sci U S A. 2003;100(2):715-720.McLaughlin B, Hartnett KA, Erhardt JA, Legos JJ, White RF, Barone FC, Aizenman E (2003) Caspase 3 activation is essential for neuroprotection in preconditioning. Proc...
该研究的结果表明,TXNIP有助于AD期间星形胶质细胞的促炎表型和caspase-3活化。 本文以题为“TXNIP contributes to induction of pro-inflammatory phenotype and caspase-3 activation in astrocytes during Alzheimer’s diseases”于2023年...
Caspase-3activationinducedbycamptothecinandetoposidedidn’tshowanapparent correlationwiththeirconcentration. Hela,HepG2andACC-Mcellsweretreatedwithcisplatin,camptothecinand etoposide.AndtheCaspase-3activitywasdetectedwithCE.Theresultsindicatedthat differentcellsshoweddistinctsensitivityuponthesamedrug.ACC-Mcellsweremore...
Caspase-3 activation is required for corticosterone-induced rat Leydig cell apoptosis Objective The high levels of corticosterone (CORT) induce apoptotic death... H You - 《Chinese Journal of Andrology》 被引量: 0发表: 2004年 Involvement of nuclear factor-kappa B on corticosterone-induced rat Leyd...
Abstract. Objectives: Nuclear factor-kappa B (NF-κB) activation has been associated with the tumorigenic growth of hepatitis B virus X protein (HBx)-transformed cells. This study was aimed to find a key target for treatment of HBx-mediated cancers. Materials and methods: NF-κB activation, ...
As was expected, Bcl-2-overexressing Mgk were remarkably resistant to caspase-3 activation induced by the depletion of thrombopoietin (TPO) from the culture. Percentages of proplatelet formation (PPF) assayed by culturing primary Mgk were slightly increased in the Tg mice. Platelet production from...
[1].Lu Cai, et al. Hyperglycemia-induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathway. Diabetes. 2002 Jun;51(6):1938-48. [2].M M Mocanu, et al. Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion...
inimprovingcurrenttherapeuticsystemsorrealizinghigher efficientcombinationaltherapies.Inthisproject,fluorescenceresonanceenergytransfer (FRET)probeCD3,which iscomposedofanenhancedcyanfluorescentprotein(CFP),a Caspase-sensitive linker,andaredfluorescentproteinfromDiscosoma(DsRed),wasused todetecttheactivationofCaspase-3in...
背景资料This Caspase-3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to prod...
Caspase-3 activation, a crucial event of neuronal cell death program, is also a feature of many chronic neurodegenerative diseases. This traditional apoptotic function of caspase-3 is challenged by recent studies that reveal new cell death-independent roles for mitochondrial-activated caspase-3 in ...