Embryoid bodies aggregated from aif-/Y ES cells did not undergo cavitation.The results suggest the existence of a second, caspase-independent, pathway for triggering apoptosis.doi:10.1186/gb-spotlight-20010403-02Kenneth LeeBioMed CentralGenome Biology...
4. Feng, S. et al. Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.Cell. Signal.19, 2056–2067 (2007). 5. Kaiser, W. J. et al. RIP3 mediates the embryonic lethality of caspase-8-deficient mice.Nature471, 368–372 (2011)....
2. Pirnia F,Schneider E, Betticher DC, Borner MM.Mitomycin C induces apoptosis andcaspase-8 and -9 processing through a caspase-3 and Fas-independent pathway.CellDeath Differ. 2002 Sep;9(9):905-14.PubMed ID: 12181741 3. Swanton E,Savory P, C...
2. Pirnia F,Schneider E, Betticher DC, Borner MM.Mitomycin C induces apoptosis andcaspase-8 and -9 processing through a caspase-3 and Fas-independent pathway.CellDeath Differ. 2002 Sep;9(9):905-14.PubMed ID: 12181741 3. Swanton E,Savory P, Cosulich S, Clarke P, Woodman P.Bcl-2 re...
(Fig.3c,dno pre-stimulation). In contrast, all BMDMs tested responded normally to cytosolic cytochrome-c, a trigger for the Apaf-1/caspase-9-dependent intrinsic apoptosis pathway (Fig.3a,c)35. Moreover,Rip3kdeficiency did not alter NLRC4-induced caspase-1-independent cell death asCasp1−/...
These results demonstrate that iodine treatment activates a caspase-independent and mitochondria-mediated apoptotic pathway. 展开 关键词: Molecular Caspaseindependent Apoptosis Carcinoma Involving Mitochondriamediated DOI: 10.1074/jbc.M600746200 被引量: 254 年份: 2006 ...
Reactive oxygen species (ROS) are generated by virus-infected cells; however, the physiological importance of ROS generated under these conditions is unclear. Here we found that the inflammation and cell death induced by exposure of mice or cells to sour
Keywords:caspase;independent;apoptosis;AIF 收稿日期:2005-03-01 作者简介:宋佰芬(1978-),女,哈尔滨人,硕士,主要从事动物分 子毒病学研究。 2005年第5期 吉林畜牧兽医 而DEVD.fmk是caspase-8抑制剂。在许多试验中,这些 抑制剂的应用对研究的现象有很大的影响。而研究者 ...
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway. Mackowiak et al., "Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway," Nature Immunology, vol. 19, no. 2, pp. 130-140, 2018.Pennemann, Friederike L.,Pichlmair,etc.Oxeiptosis, ...
5) Apoptosis pathway 凋亡途径 例句>> 6) Caspase-independent Caspase非依赖性 补充资料:细胞凋亡 分子式: CAS号: 性质:是细胞的一种不同于坏死的死亡方式,是由基因控制的细胞自我消亡过程,是一连串精确的生化变化的结果,不像坏死是意外事件使细胞受损伤的消极结果,其发生为机体维持衡态所需,因而有积极的生物学...