In conclusion, the impaired neurogenesis and activated caspase 3-dependent apoptosis pathway in the RVLM might be involved in hypertension in SHRSP.doi:10.1096/fasebj.22.1_supplement.1234.5Takuya KishiCardiovascular MedicineKyushu UniversityFukuokaJapanYoshitaka Hirooka...
[3]Resveratrol,a tumor-suppressive compound from grapes induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.Tinhofer I,Bernhard D,Senfter M,et al.The FASEB Journal.2001 [4]Bcl-2 overexpression attenuates resveratrol-induced apoptosis in U937 cells by inhibition of caspase-3 act...
Mol Cell. 1998Jun;1(7):949-57.PubMed ID: 9651578 2. Pirnia F,Schneider E, Betticher DC, Borner MM.Mitomycin C induces apoptosis andcaspase-8 and -9 processing through a caspase-3 and Fas-independent pathway.CellDeath Differ. 2002 Sep;9(9):9...
《Overexpression of hsa_circ_0007534 predicts unfavorable prognosis for osteosarcoma and regulates cell growth and apoptosis by affecting AKT/GSK-3β signaling pathway》 作者:Baoquan Li,Xiaoguang Li 期刊:Biomedicine & Pharmacotherapy 影响因子:3.743 PMID:30142548 ...
3.3Caspase-3 and TRX system Caspase-3 is an enzyme that induces apoptosis. S-nitrosylation of a cysteine residue on caspase-3 can inhibit its activity in endothelial cells[64,74–76]. Thus, eNOS-derived NO could potentially inhibit its activity and subsequently block apoptosis in endothelial cel...
pathway response to glucocorticoid neuron apoptotic process cellular response to organic cyclic compound apoptotic signaling pathway extrinsic apoptotic signaling pathway in absence of ligand execution phase of apoptosis response to wounding intracellular signal transduction positive regulation of apopto...
细胞凋亡(Apoptosis) 细胞凋亡有两条途径:内在途径(Intrinsic pathway)和外在途径(Extrinsic pathway)。 内在途径也称为线粒体途径,受BCL-2家族调控。在这一途径中,BCL-2家族成员BAX和/或BAK的激活允许凋亡效应因子渗透线粒体外膜,导致细胞色素c进入细胞质,并在此与APAF-1结合,触发凋亡小体的形成。该凋亡小体首先...
免疫原 Caspase 3/P17/P19 fusion protein Ag25029 种属同源性预测 宿主/亚型 Mouse / IgG1 抗体类别 Monoclonal 产品类型 Antibody 全称 caspase 3, apoptosis-related cysteine peptidase 别名 CASP3, Caspase3, Caspase 3, CASP-3, CASP 3 计算分子量 277 aa, 32 kDa 观测分子量 32-35 kDa, 19 kDa,...
2、述。 关键词:Caspase;细胞凋亡 细胞凋亡的原词Apoptosis由两个拉丁字组成。Apo指离开,ptosis是落下,意思是细胞凋亡有如秋天落叶,到一定时候即失去生命力,遂即脱落,细胞凋亡,又称程序性细胞死亡(Programmed cell death,PCD)是机体生长发育、细胞分化和病理状态中细胞自主性死亡过程,是细胞内由基因编码调控的,按严格...
Caspase-3-dependent cell death pattern Apoptosis Apoptosis is a non-inflammatory form of programmed cell death (PCD) mediated by activation of the apoptotic caspases and can occur either via an intrinsic or an extrinsic pathway4. The intrinsic pathway is activated by mitochondrial damage. Subsequently...