6e–h). The lack of effect of PDK1, PDK3 and PDK4 silencing on PDHA1 phosphorylation was not due to any compensation by PDK2 expression, as PDK2 protein levels were unaffected (Extended Data Fig. 6i). Overexpression of PDK2 wild type (PDK2WT), but not a mutant enzymatically inactive...
Content type: Research 14 April 2025 Single-cell and spatial transcriptomic analyses revealing tumor microenvironment remodeling after neoadjuvant chemoimmunotherapy in non-small cell lung cancer Authors: Xiaolu Cui, Siyuan Liu, He Song, Jingjing Xu and Yanbin Sun Content type: Research 9 April 2025...
Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is a heterogeneous and aggressive type of T-cell lymphoma. Here, the authors perform single-cell analyses of human and murine PTCL-NOS tumors, and identify a subtype defined by the loss of SMARCB1 that could be targeted with HDAC...
As the official journal of the International Cancer Imaging Society, and written by renowned international experts in the field, Cancer Imaging encompasses ...
Journal of Experimental and Clinical Cancer Research is ranked in the first quartile of oncology journals in Journal Citation Reports and is the official ...
Table 4. Age-standardized mortality rates for cancer, overall, by area and cancer type by geographic areas covered by 487 cancer registries, 2016 (1/105). Geographic areasAll sitesEsophagusStomachColorectumLiverLungFemale breastCervixProstateKidneyBladderLymphomaLeukemia All areas 104.5 8.5 12.4 7.9 15...
endoscopy, single balloon endoscopy, Spiral outer tube type enteroscopy, endoscopic narrowband imaging technique, auto-fluorescence endoscopic diagnosis technique and endoscopic mucosal dissection (ESD) for early gastrointestinal cancer ...
Researchers discovered that some cancers grouped together based on the cell type from which the tumor came from. For example, squamous cell cancers from the head and neck, lung, and bladder, cervix, and esophagus had strong molecular similarities and grouped together. ...
It's worth noting that we also made an intriguing discovery regarding pCAFs, which exhibited heightened activity in IFN-I production. The role of IFN-I (Type I interferon) in cancer presents a dual-edged sword effect [59,60,61,62,63]. Acute exposure to high concentrations of IFN-I can...
“Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation”. Cancer Research 1992; 52:4168–4174. CAS Google Scholar Wogan GN and Tannenbaum S. “Biological Monitoring of Environmental Toxic Chemicals” In: Lave LB and Upton AC (Eds)...