In addition, the limited repertoire of available drugs has made it difficult to exploit these differences for different treatment strategies.BerndGronerGroner B. Introduction: The rationale for the development of targeted drugs in cancer therapy. Recent Results Cancer Res 2007; 172:1‑3....
Targeted therapy drugs work in a few different ways. They may turn off the process in cancer cells that causes them to grow and spread, making cancer cells die on their own or kill cancer cells directly. People with the same type of cancer may have different targets in their cancer cells...
Targeted therapy(靶向治疗)uses drugs to stopcancer from growing and spreading. It's a newfor all patients with cancer. At the same time,effective way that is better than other treatmentsdifferent cancers may have the same target.chemotherapy according to the text?With the development of targeted...
If the right target is present inthe patient's cancer, then they will receive thetreatment In most cases, patients will receive targetedtherapy along with some other treatments likechemotherapy or radiation therapy(放射性治疗).And they may receive these drugs as part of theirregular treatment.28....
New antineoplastic agents approved by the FDA for a variety of cancers advance drug therapy as more research spurs the fast pace of change in oncology. “Targeted therapy” is all the buzz in oncology circles lately. Targeting tumors at cellular levels creates more effective therapies—often with...
Targeted cancer therapy is administered with two primary types of medications: Small moleculedrugs: Small molecule drugs are tiny particles that can work on the surface of the cells and can also get into the cell and work on the proteins and signaling pathways inside the cancer cell. ...
Translating cancer research into targeted therapeutics. The emphasis in cancer drug development has shifted from cytotoxic, non-specific chemotherapies to molecularly targeted, rationally designed drugs promisin... JSD Bono,A Ashworth - 《Nature》 被引量: 468发表: 2010年 The use of targeted mouse ...
Overview of the development status of mitochondrially-targeted drugs (PDF 817 kb) Glossary Intrinsic pathway of apoptosis Also known as mitochondrial apoptosis, it is triggered by intracellular stimuli such as Ca2+ overload and overproduction of reactive oxygen species. By contrast, extrinsic apoptosis...
Colon cancer therapy: recent developments in nanomedicine to improve the efficacy of conventional chemotherapeutic drugs. The number of patients with colorectal cancer, the third most frequently diagnosed malignancy in the world, has increased markedly over the past 20 years a... J,Prados,C,... ...
drugs is quite troublesome, given that palliation is the primary goal of oncology therapy. Recently, oncology therapy has migrated to the use of small molecules targeting intracellular events specific to tumor cells. The era of “targeted therapy” was heralded by the approval of the antibodies ...