This has individualized medical care for the cancer patient. From the regulatory perspective, targeted therapy involves a drug in whose approval label there is a specific reference to a simultaneously or previously approved diagnostic test. This test must be performed before the patient can be ...
The lessons learned from the use of these therapeutics will add to the growing knowledge of mechanistic approaches to the treatment of patients with cancer based upon targeted therapies, and herald a bright future that will improve the lives of patients with cancer. 展开 关键词:...
Several therapeutic modalities, such as surgery, radiation therapy, and systemic anticancer therapy, have been applied clinically for cancer treatment, either alone, in combination, or sequentially, depending on the stage, resectability, biology, comorbidities, and patient’s overall functional performance3...
“We can use BPGAP1 as both a marker for cancer prognosis and a target for cancer intervention across different cancer types,” said the researchers, “We hope that with this breakthrough, we can inspire new approaches for therapeutic designs pertaining to cancer and metastasis.”...
Sessa C, Del Conte G. Targeted therapies: tailored treatment for ovarian cancer: are we there yet? Nat Rev Clin Oncol 2010; 7(2): 80-2. http://dx.doi.org/10.1038/nrclinonc.2009.233Conte G. Targeted therapies: tailored treatment for ovarian cancer: are we there yet? Nat Rev Clin ...
In this chapter, we discuss what are the major receptors overexpressed in tumor cells and how these receptors have been widely tested as a targeted therapy in the treatment of cancer. We discuss the main classes of immunotherapy, including monoclonal ant
Advanced and recurrent gynecological cancers are associated with poor prognosis and lack of effective treatment. The developments of the molecular mechanisms on cancer progression provide insight into novel targeted therapies, which are emerging as groundbreaking and promising cancer treatment strategies. In ...
HER2 targeted therapies in different cancer Breast cancer Antibodies The introduction of HER2-targeted therapy has revolutionized the landscape of breast cancer treatment. The currently approved HER2 monoclonal antibodies (mAb) for breast cancer treatment include trastuzumab and pertuzumab. Trastuzumab (Hercept...
Targeted therapies can better treat manycells that causes them to grow and spread, makingthe patient's cancer, then they will receive thecertain kinds of cancers.cancer cells die on their own or kill cancer cellstreatment. In most cases, patients will receive6. What's the author's purpose ...
Common to all these targeted therapies is their interaction with defined molecules present on cancer cells, which adds various degrees of increased selectivity to their toxic effects. As a consequence, detecting the target molecule on tumors before therapy holds great diagnostic potential for predicting...