mRNA vaccines have been revolutionary in terms of their rapid development and prevention of SARS-CoV-2 infections during the COVID-19 pandemic, and this technology has considerable potential for application to the treatment of cancer. Compared with traditional cancer vaccines based on proteins or pept...
Based on the above characteristics and the development of mRNA vaccines, mRNA cancer vaccines have become a research hotspot and have undergone rapid development, especially in the last five years. This review analyzes the advances in mRNA cancer vaccines from various perspectives, including the ...
Research on mRNA vaccines has been continuing, following their successful approval for COVID-19. Now, scientists from Beijing have published in the journalNano Lettersthat they are working towards an mRNA vaccine for some cancers. Their injectable hydrogel was testing in mice with melanoma. The vac...
mRNA vaccines have become a promising platform for cancer immunotherapy. During vaccination, naked or vehicle loaded mRNA vaccines efficiently express tumor antigens in antigen-presenting cells (APCs), facilitate APC activation and innate/adaptive immune stimulation. mRNA cancer vaccine precedes other ...
been working on mRNA vaccines to treat or prevent other diseases, including some forms of cancer. Now, researchers reporting inACS’Nano Lettershave developed a hydrogel that, when injected into mice with melanoma, slowly released RNA nanovaccines that shrank tumors and kept them from metastasizing...
格林解释说,为了使传染病和非传染病(如癌症)的疫苗更加强大,需要纳米粒子的mRNA内容到达、进入并在树突状细胞中表达。研究人员说,当mRNA在树突状细胞中表达后,它会被迅速降解,而由此产生的免疫细胞反应在mRNA和纳米颗粒早已消失后可以持续很长时间。 通常情况下,科学家们通过在纳米粒子上附加蛋白质来完成这种细胞定位...
There are two main types of mRNA vaccines: non-replicating mRNA vaccine and self-amplifying mRNA vaccine [45]. The action mechanism of cancer mRNA vaccine Each step in the process of developing an mRNA vaccine is critical. As mRNA cancer vaccine evolves toward individualized medicine, the identif...
mRNA vaccines have become a promising platform for cancer immunotherapy. During vaccination, naked or vehicle loaded mRNA vaccines efficiently express tumor antigens in antigen-presenting cells (APCs), facilitate APC activation and innate/adaptive immune stimulation. mRNA cancer vaccine precedes other conve...
2024年10月9日,吉林大学崔久嵬团队在Molecular Cancer在线发表题为“Advances and applications of RNA vaccines in tumor treatment”的综述,该综述阐述了RNA疫苗在抗肿瘤治疗中的研究进展及应用。还讨论了将这一有前景的疫苗平台扩展到广泛...
cell lung cancer (NSCLC). Most of the world became familiar with mRNA vaccines during COVID-19, the first time mRNA vaccines were commercially developed. Now, there's great hope that mRNA cancer vaccines could provide an alternate treatment to eradicate cancer cells and keep them away for ...