所以，mRNA疫苗也被认为是未来癌症治疗领域最有希望的候选治疗药物，特别是将mRNA疫苗和其他免疫疗法组合，比如目前大火的PD-1抑制剂。基于mRNA的疫苗作用模式 二、肺癌mRNA疫苗联合PD-1的临床项目 ABOR2013是一款针对肺癌的mRNA疫苗，这是广州呼吸健康研究院与艾博生物联合自主开发的针对肺癌新生抗原的治疗型mRNA肿瘤疫苗...
10月1日，Inge Marie Svane等人在柳叶刀官网发表题为 “Clinical advances and ongoing trials of mRNA vaccines for cancer treatment” 的综述文章，回顾了mRNA癌症疫苗的临床研究现状。在上一篇推文中，我们已经介绍了裸露的mRNA癌症疫苗、鱼精蛋白封装的mRNA癌症疫苗以及mRNA脂质复合体疫苗相关的最新临床研究进展，欢迎...
[2] Lorentzen CL, Haanen JB, Met Ö, Svane IM. Clinical advances and ongoing trials on mRNA vaccines for cancer treatment. Lancet Oncol. 2022 Oct;23(10):e450-e458. doi: 10.1016/S1470-2045(22)00372-2.[3] Thiago Carvalho. Personalized anti-cancer vaccine combining mRNA and immunotherapy...
Lorentzen CL, et al, Clinical advances and ongoing trials on mRNA vaccines for cancer treatment. Lancet Oncol. 2022 Oct;23
mRNA Cancer Vaccines: Construction and Boosting Strategies. ACS Nano. 2023 Oct 24;17(20):19550-19580. doi: 10.1021/acsnano.3c05635. [2] Lorentzen CL, Haanen JB, Met Ö, Svane IM. Clinical advances and ongoing trials on mRNA vaccines for cancer treatment. Lancet Oncol. 2022 Oct;23(10...
本文摘编自The Lancet Oncology期刊于10月1日发表的题为:Clinical advances and ongoing trials of mRNA vaccines for cancer treatment 的综述文章,因原文篇幅过长,脂质纳米颗粒mRNA疫苗、mRNA-树突细胞癌症疫苗和mRNA癌症疫苗面临的挑战和未来展望等内容将在后续文章...
特别备注：本文摘编自柳叶刀官网10月1日发表的题为 “Clinical advances and ongoing trials of mRNA vaccines for cancer treatment” 的综述文章，因原文篇幅过长，脂质纳米颗粒mRNA疫苗、mRNA-树突细胞癌症疫苗和mRNA癌症疫苗面临的挑战和未来展望等内容将在下一期文章中发布。参考资料 [1] Lorentzen, Cathrine Lund, ...
2022年10月,哥本哈根大学Inge Marie Svane作为通讯作者在Lancet Oncol期刊(IF: 54.433)发表综述文章《Clinical advances and ongoing trials on mRNA vaccines for cancer treatment》,基于mRNA递送系统分类,对当前mRNA肿瘤治疗性疫苗的临床研究现状进行了深度回顾。
本文摘编自 The Lancet Oncology 期刊于10月1日发表的题为:Clinical advances and ongoing trials of mRNA vaccines for cancer treatment 的综述文章,因原文篇幅过长,脂质纳米颗粒mRNA疫苗、mRNA-树突细胞癌症疫苗和mRNA癌症疫苗面临的挑战和未来展望等内容将在后续文章中发布。
Summary The development of mRNA vaccines represents a significant advancement in cancer treatment, with more than 120 clinical trials to date demonstrating their potential across various malignancies, including lung, breast, prostate, melanoma, and more challenging cancers such as pancreatic and brain ...