aPositive results for drug combo in I-SPY 2 trial. 正面结果为药物组合在I-SPY 2试验。 [translate] aHeight, body mass index (BMI), BMI change, and the risk of estrogen receptor-positive, HER2-positive, and triple-negative breast cancer among women ages 20 to 44 years. 高度、身体许多索引...
HER2: Human epidermal growth factor receptor 2 APRI: Aspartate transaminase–to-platelet ratio index ML: Machine learning CNN: Convolutional-neural-network RNN: Recurrent-neural-network DCNN: Deep convolutional neural network LSTM: Long short-term memory DCNN-US: Deep convolutional neural net...
Particularly patients with early breast cancer (EBC) and low risk factors are unlikely to suffer distant metastases [4]. Hormone receptor-positive, HER2 negative, and node-negative breast cancer with low tumor stage, indicate a favorable prognosis [5]. Breast cancer primarily spreads via the ...
Using a computational technique, the team grouped together cancer cells in which similar sets of genes were turned on or off and found there were actually 10 categories of breast cancer cells. Just three categories of breast cancer cells (hormone-positive, HER2-positive, and triple-negative) are...
node-negative women with early stage ER-positive tumors treated with tamoxifen have the best prognosis, but this population also receives a small, but significant, benefit from chemotherapy.7 Adverse drug effects also vary by drug and regimen, but can have a well-described negative impact on pati...
In patients with HER2-positive or triple-negative metastatic breast cancer, the average symptom severity scores were significantly lower than those observed in patients with estrogen receptor/progesterone receptor-positive or HER2-negative metastatic breast cancer (p=0.033). Patients in the fourth-line ...
Progesterone Receptor (PR): PositiveTumor cells with nuclear positivity: 90% Average intensity of staining: 3+ Her2 by IHC: Negative Score: 0 Ki67: 10% SMM: Negative Three days ago I had my breast biopsy. Yes, again with the damn MRI machine bangy-bangy bullshit. ...
Here, we developed and validated a new prognostic model for predicting the risk of distant metastasis in patients with pN0-N1, hormone receptor-positive, HER2-negative (HR+/ HER2−) breast cancer treated with hormone therapy alone. RNA was extracted from formalin- fixed, paraffin-embedded ...
We report a patient with advanced hormone-positive, HER2-negative breast cancer with contralateral supraclavicular node and subpleural lung nodules who was treated with letrozole and palbociclib with palliative intent. After 2years of treatment, PET–CT showed disease confined only to the breast and ...
many international cohorts of cancer patients have shown negative prognostic value for TAMs expressing CD68, CD163, CD204, CD206, MARCO, and stabilin-1 [9,28]. In several in vitro and in vivo studies, both the pro- and antitumor activities of SRs have been demonstrated to be dependent on...