Calcium is coordinated by a pentagonal bipyramidal arrangement of oxygen atoms, six of which are provided by intradomain ligands. Each individual cbEGF domain contains a weak calcium-binding site, the affinity of which may be substantially enhanced by N-terminal linkage to another domain. Structural...
Calcium is coordinated by a pentagonal bipyramidal arrangement of oxygen atoms, six of which are provided by intradomain ligands. Each individual cbEGF domain contains a weak calcium-binding site, the affinity of which may be substantially enhanced by N-terminal linkage to another domain. Structural...
产品名称:Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) ELIS 产品型号:abx576671 产品展商:其它品牌 产品文档:无相关文档 简单介绍 Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) ELISA Kit ...
The known roles for calcium-binding proteins in developmental signaling pathways are reviewed. Current information on the calcium-binding characteristics of three classes of cell-surface developmental signaling proteins (EGF-domain proteins, cadherins and integrins) is presented together with an overview of...
egf-likecalcium-bindingsite网络表皮生长因子样钙结合位点 网络释义 1. 表皮生长因子样钙结合位点 ...表皮生长因子功能域(EGFlikedomain)和表皮生长因子样钙结合位点(EGF-likecalcium-bindingsite),与Fibrillin蛋白家族的特点 …new.med.wanfangdata.com.cn|基于1 个网页©...
Calcium predominantly increases low strain cbEGF domain stiffness Given the essential role calcium plays in fibrillin-1 microfibrils, which serve as integral components of stretchable elastic fibers4,5, we were first interested in determining how wild-type cbEGF domains deform under mechanical stress ...
However, the effect on 3H-gabapentin binding was not reproduced by the synaptogenic EGF-domain of thrombospondin-4. Partial co-immunoprecipitation could be demonstrated between thrombospondin-4 and α2δ-1 when co-transfected, but there was no co- immunoprecipitation with thrombospondin-4-EGF domain...
EGF: epidermal growth factor ER: endoplasmic reticulum FTDP-17: frontotemporal dementia and parkinsonism linked to chromosome 17 GPCR: G-protein coupled receptors HNF4α: hepatocyte nuclear factor 4α Ig: immunoglobulin ITAM: immunoreceptor tyrosine based activation motif iNOS: inducible nitric...
Calcium is coordinated by a pentagonal bipyramidal arrangement of oxygen atoms, six of which are provided by intradomain ligands. Each individual cbEGF domain contains a weak calcium-binding site, the affinity of which may be substantially enhanced by N-terminal linkage to another domain. Structural...
domainEGFextracellularmoduleproteinEpidermal growth factor-like (EGF) domains are one of the more abundant modules found in functionally diverse extracellular proteins. The domain is characterized by six cysteine residues, which normally disulphide bond in a 1–3, 2–4, 5–6 pattern. A particular ...